SIGLEC15 (PYX-106 Biosimilar) Recombinant Monoclonal Antibody
-
貨號:CSB-RA761623MB2HU
-
規格:¥83486
-
其他:
產品詳情
-
產品描述:SIGLEC15 (PYX-106 Biosimilar Antibody)重組單克隆抗體是一種專為科研用途開發的生物試劑,旨在為生命科學研究提供高特異性的分子工具。該抗體針對SIGLEC15(唾液酸結合免疫球蛋白樣凝集素15)設計,通過重組DNA技術在哺乳動物細胞表達系統中制備,確保了產品的高純度和批次間穩定性。 SIGLEC15作為一種跨膜蛋白,在免疫調節、腫瘤微環境及炎癥反應中發揮重要作用。研究表明,其在多種腫瘤組織中異常表達,可能參與免疫抑制性微環境的形成,因此成為腫瘤免疫治療機制研究的潛在靶點。本產品可用于等多種實驗方法,助力科研人員深入探究SIGLEC15的生物學功能及其在疾病發生發展中的作用機制。 該重組單克隆抗體經過嚴格的質量控制,包括抗體純度檢測(SDS-PAGE和HPLC分析)、特異性驗證(ELISA和實驗)以及活性評估,確保在科研應用中具有高靈敏度和低背景干擾。產品提供液體形式,可直接用于實驗或根據需要進行稀釋,使用方便且操作靈活。 作為科研用試劑,SIGLEC15 (PYX-106 Biosimilar Antibody)重組單克隆抗體為免疫學、腫瘤生物學、細胞生物學等領域的基礎研究和轉化醫學研究提供了可靠的實驗材料,有助于推動相關疾病機制的深入探索及潛在治療靶點的發現。
-
Uniprot No.:
-
基因名:
-
別名:Anti-Siglec-15 monoclonal antibodies(Biosion, Inc.) research-grade biosimilar; Anti-siglec15 monoclonal antibody (Biosion) research-grade biosimilar; BSI060T research-grade biosimilar; BSI 060T research-grade biosimilar; BSI-060T research-grade biosimilar; BSI- 060T research-grade biosimilar; PYX-106 research-grade biosimilar ;SIGLEC15 antibody; CD33L3 antibody; Sialic acid-binding Ig-like lectin 15 antibody; Siglec-15 antibody; CD33 antigen-like 3 antibody
-
反應種屬:Human
-
免疫原:Recombinant Human SIGLEC15 protein
-
免疫原種屬:Homo sapiens (Human)
-
標記方式:Non-conjugated
-
克隆類型:Monoclonal
-
濃度:It differs from different batches. Please contact us to confirm it.
-
保存緩沖液:0.01M PBS,pH7.4
-
產品提供形式:Liquid
-
應用說明:Validation Status
Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
Guaranteed Quality
① Antibody purity?> 95% tested by SDS-PAGE.
② Endotoxin level < 0.1EU/ug tested by LAL method. -
儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
貨期:3-4 weeks
-
用途:It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.
相關產品
靶點詳情
-
功能:Binds sialylated glycoproteins.
-
基因功能參考文獻:
- Siglec-15 recognizes the tumoral sTn antigen and transduces a signal for enhanced TGF-beta secretion in TAMs PMID: 23035012
-
亞細胞定位:Membrane; Single-pass type I membrane protein.
-
蛋白家族:Immunoglobulin superfamily, SIGLEC (sialic acid binding Ig-like lectin) family
-
組織特異性:Expressed in macrophage and/or dendritic cells of spleen and lymph nodes.
-
數據庫鏈接:
Most popular with customers
-
-
Phospho-YAP1 (S127) Recombinant Monoclonal Antibody
Applications: ELISA, WB, IHC
Species Reactivity: Human
-
-
-
-
-
-















