Recombinant Rat Gamma-butyrobetaine dioxygenase (Bbox1)

中文名稱：

Recombinant Rat Gamma-butyrobetaine dioxygenase(Bbox1)
貨號：

CSB-YP870793RA
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Rat Gamma-butyrobetaine dioxygenase(Bbox1)
貨號：

CSB-EP870793RA
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Rat Gamma-butyrobetaine dioxygenase(Bbox1)
貨號：

CSB-EP870793RA-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Rat Gamma-butyrobetaine dioxygenase(Bbox1)
貨號：

CSB-BP870793RA
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Rat Gamma-butyrobetaine dioxygenase(Bbox1)
貨號：

CSB-MP870793RA
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Bbox1
Uniprot No.：

Q9QZU7
別名：

Bbox1; Bbh; Gamma-butyrobetaine dioxygenase; EC 1.14.11.1; Gamma-butyrobetaine hydroxylase; Gamma-BBH; Gamma-butyrobetaine,2-oxoglutarate dioxygenase
種屬：

Rattus norvegicus (Rat)
蛋白長度：

full length protein
表達區域：

1-387
氨基酸序列

MHCAILKAEA VDGARLMQIF WHDGAESLYP AVWLRDNCQC SDCYLHSAKA RKLLLEALDV NIRMDDLTFD QKKVYITWPN GHYSEFEANW LKKRCFSQEA RAGLQGELFL PECQYWGSEL QLPTLNFEDV LNDDDHAYKW LSSLKKVGIV RLTGAADKRG EIIKLGKRIG FLYLTFYGHT WQVQDKIDAN NVAYTTGKLS FHTDYPALHH PPGVQLLHCI KQTVTGGDSE IVDGFNVCQK LKEKNPQAFS ILSSTFVDFT DIGVDYCDFS VQSKHKIIEL DDKGQVVRIN FNNATRDTVF DVPIERVQPF YAALKEFVDL MNSKEYKYTF KMNPGDVITF DNWRLLHGRR SYEAGTEISR HLEGAYADWD VVMSRLRILR QRVMNGN
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Catalyzes the formation of L-carnitine from gamma-butyrobetaine.
基因功能參考文獻：
1. Data suggest that expression of BBH mRNA and protein is up-regulated in liver with training in physical activity; in kidney, only BBH mRNA expression is up-regulated. PMID: 22014179
2. Thyroid hormone controls carnitine status through modifications of gamma-butyrobetaine hydroxylase activity and gene expression PMID: 11964131
3. Alterations in enzyme activities in the pivalate-treated rats are not regulated at the transcriptional level, and are apparently related to post-transcriptional effects on the enzymes themselves. PMID: 15795431
4. BBH mRNA, however, was detected during the suckling period onwards and its abundance was not changed significantly by maturation PMID: 19150623
亞細胞定位：

Cytoplasm.
蛋白家族：

Gamma-BBH/TMLD family
組織特異性：

Expressed in the liver and in some extend in the testis and the epididymis.
數據庫鏈接：

KEGG: rno:64564

STRING: 10116.ENSRNOP00000006197

UniGene: Rn.16333