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VEGFC

VEGFC,全稱為血管內皮生長因子C,是一種重要的血管生成和淋巴管生成因子。它也被稱為VEGF-C、VEGF C、血管內皮生長因子相關蛋白、Flt4-Ligand等。VEGFC主要作用于淋巴管內皮細胞,通過其受體VEGFR-3促進淋巴管的生長、存活和遷移,從而在淋巴管生成中發揮關鍵作用。VEGFC在胚胎發育和成人淋巴管系統的維持中均扮演重要角色。VEGFC的過度表達可能導致淋巴管擴張,進而可能促進腫瘤的轉移。VEGFC已成為抗腫瘤治療的重要靶點,針對VEGFC的藥物研發已取得顯著進展。例如,信達生物研發的抗VEGF-A/VEGF-C雙特異性抗體IBI333已在國內獲批臨床,用于治療新生血管性年齡相關性黃斑變性。IBI333通過同時靶向VEGF-A和VEGF-C,能夠更有效地抑制血管新生和改善血管滲漏,為VEGFC相關疾病的治療提供了新的選擇。

熱銷產品

Recombinant Human Vascular endothelial growth factor C (VEGFC) (CSB-EP025835HU)

驗證數據

CSB-EP025835HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

VEGFC Antibody (CSB-PA07545A0Rb)

驗證數據

CSB-PA07545A0Rb

Western Blot
Positive WB detected in: 293T whole cell lysate
All lanes: VEGFC antibody at 2µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/15000 dilution
Predicted band size: 47 kDa
Observed band size: 47 kDa

CSB-PA07545A0Rb

Immunohistochemistry of paraffin-embedded human lung cancer using CSB-PA07545A0Rb at dilution of 1:100

Human Vascular Endothelial cell Growth Factor C,VEGF-C ELISA KIT (CSB-E04759h)

驗證數據

CSB-E04759h 標準曲線

貨號:CSB-E04759h

規格:96T/48T

靈敏度:3.9 pg/mL

檢測范圍:15.6 pg/mL-1000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

VEGFC Antibodies

VEGFC for Homo sapiens (Human)

VEGFC for Mus musculus (Mouse)

VEGFC Proteins

VEGFC Proteins for Mus musculus (Mouse)

VEGFC Proteins for Homo sapiens (Human)

VEGFC Proteins for Rattus norvegicus (Rat)

VEGFC ELISA Kit

VEGFC ELISA Kit for Homo sapiens (Human)

VEGFC ELISA Kit for Mus musculus (Mouse)



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