TRIB3
TRIB3，即Tribbles同源蛋白3，它是一種在多種細胞類型中表達的假激酶。TRIB3能夠與多種蛋白質相互作用，參與調節(jié)細胞的代謝、應激反應、炎癥以及細胞周期等過程。其作用機制包括通過與Akt等蛋白結合并影響其活性，進而調控細胞的生存和代謝。在信號通路方面，TRIB3與PI3K-AKT-mTOR信號通路密切相關，它通過抑制Akt的磷酸化和活性，參與調節(jié)細胞的代謝和存活。在生物學意義上，TRIB3在糖尿病、癌癥、心血管疾病和神經系統(tǒng)疾病的發(fā)生發(fā)展中可能發(fā)揮重要作用。研究表明，TRIB3的表達受多種應激反應的調控，如營養(yǎng)缺乏、缺氧、內質網應激等，提示其在細胞應激反應中的"橋梁"作用。
熱銷產品
Recombinant Mouse Tribbles homolog 3 (Trib3) (CSB-EP818358MO)
驗證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
TRIB3 Antibody (CSB-PA847220LA01HU)
驗證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA847220LA01HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human pancreatic tissue using CSB-PA847220LA01HU at dilution of 1:100
TRIB3 Antibodies
TRIB3 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA024446GA01HU | TRIB3 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA120599 | TRIB3 Antibody | Human | ELISA,IHC |
| CSB-PA592034 | TRIB3 Antibody | Human | ELISA,IHC |
| CSB-PA847220LA01HU | TRIB3 Antibody | Human | ELISA, IHC |
| CSB-PA847220LB01HU | TRIB3 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA847220LC01HU | TRIB3 Antibody, FITC conjugated | Human | |
| CSB-PA847220LD01HU | TRIB3 Antibody, Biotin conjugated | Human | ELISA |
TRIB3 Proteins
TRIB3 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP847220HU CSB-EP847220HU CSB-BP847220HU CSB-MP847220HU CSB-EP847220HU-B |
Recombinant Human Tribbles homolog 3 (TRIB3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
