THAP11

THAP11，全稱為THAP結(jié)構(gòu)域包含蛋白11，是一種在視網(wǎng)膜早期發(fā)育中起重要作用的蛋白質(zhì)。它能夠防止視網(wǎng)膜祖細胞過早退出細胞周期，從而促進視網(wǎng)膜的正常發(fā)育。THAP11蛋白也被稱為CTG-B43a、CTG-B45d、HRIHFB2206和RONIN等。研究表明，THAP11蛋白的突變會導致小腦神經(jīng)元死亡，并引發(fā)神經(jīng)炎癥，進而導致神經(jīng)元的損傷和死亡。這一發(fā)現(xiàn)為治療SCA51神經(jīng)退行性疾病提供了新的潛在靶點。目前，針對THAP11蛋白的藥物研發(fā)尚處于起步階段，但已有研究表明，靶向THAP11或小膠質(zhì)細胞活化通路有望成為治療SCA51的潛在策略。

熱銷產(chǎn)品

Recombinant Human THAP domain-containing protein 11 (THAP11), partial (CSB-EP846612HU)

驗證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

THAP11 Antibody

THAP11 Protein

THAP11 Antibodies

THAP11 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應性	應用類型
CSB-PA846612LA01HU	THAP11 Antibody	Human	ELISA

THAP11 Proteins

THAP11 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP846612HU CSB-BP846612HU CSB-MP846612HU CSB-EP846612HU-B	Recombinant Human THAP domain-containing protein 11 (THAP11)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP846612HU	Recombinant Human THAP domain-containing protein 11 (THAP11), partial	E.coli