TBC1D31
TBC1D31，即TBC1結(jié)構(gòu)域家族成員31。別名Gm85、WDR67等。它在人類細(xì)胞中廣泛表達(dá)，尤其在睪丸、淋巴結(jié)等組織中表達(dá)量較高。TBC1D31的作用機(jī)制涉及到其作為Rab GTPase活化蛋白，通過(guò)催化Rab22A的GTP水解，減少Rab22A介導(dǎo)的溶酶體內(nèi)運(yùn)輸和EGFR降解，從而激活EGFR信號(hào)傳導(dǎo)，并在肝細(xì)胞癌中發(fā)揮作用。TBC1D31可作為一個(gè)新的治療靶點(diǎn)，用于治療TBC1D31基因擴(kuò)增或過(guò)表達(dá)的肝細(xì)胞癌患者。
熱銷產(chǎn)品
TBC1D31 Antibody (CSB-PA822197LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry analysis of human testis tissue using CSB-PA822197LA01HU at dilution of 1:100
Immunocytochemistry analysis of human glioma using CSB-PA822197LA01HU at dilution of 1:100
TBC1D31 Antibodies
TBC1D31 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA822197LA01HU | TBC1D31 Antibody | Human | ELISA, IHC |
| CSB-PA822197LB01HU | TBC1D31 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA822197LD01HU | TBC1D31 Antibody, Biotin conjugated | Human | ELISA |
TBC1D31 Proteins
TBC1D31 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP822197HU CSB-EP822197HU CSB-BP822197HU CSB-MP822197HU CSB-EP822197HU-B |
Recombinant Human WD repeat-containing protein 67 (WDR67), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
