TARDBP

TARDBP蛋白，也稱為TDP-43，是一種具有RRM1和RRM2的RNA結合因子，其結構包括N端的氨基末端、兩個RNA識別區以及富含甘氨酸的C端。該蛋白通過結合GU重復序列，調節RNA的剪接過程，對神經元存活和神經退行性疾病中的蛋白質功能至關重要。TARDBP蛋白的突變或異常聚集與多種神經退行性疾病如ALS和FTLD相關。雖然其具體的信號通路尚未完全明確，但研究表明，TARDBP可能與其他蛋白或分子相互作用，形成復雜的信號網絡，共同調控神經元的生存和功能，涉及細胞凋亡、自噬等信號轉導途徑。

熱銷產品

Recombinant Human TAR DNA-binding protein 43 (TARDBP), partial

驗證數據

SDS

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

TARDBP Antibody

TARDBP Protein

TARDBP ELISA Kit

TARDBP Antibodies

TARDBP for Homo sapiens (Human)

產品貨號	產品名稱	種屬反應性	應用類型
CSB-PA023129GA01HU	TARDBP Antibody	Human,Mouse,Rat,Zebrafish	ELISA,WB,IHC,IF,IP
CSB-PA621652ESR1HU	TARDBP Antibody	Human, Mouse	ELISA, WB, IHC, IP
CSB-PA023129EA01HU	TARDBP Antibody	Human	ELISA, WB, IHC, IF
CSB-PA023129EB01HU	TARDBP Antibody, HRP conjugated	Human	ELISA
CSB-PA023129EC01HU	TARDBP Antibody, FITC conjugated	Human
CSB-PA023129ED01HU	TARDBP Antibody, Biotin conjugated	Human	ELISA

TARDBP Proteins

TARDBP Proteins for Homo sapiens (Human)

產品貨號	產品名稱	來源
CSB-EP023129HU	Recombinant Human TAR DNA-binding protein 43 (TARDBP), partial	E.coli
CSB-YP023129HU	Recombinant Human TAR DNA-binding protein 43 (TARDBP), partial	Yeast
CSB-EP023129HUe0	Recombinant Human TAR DNA-binding protein 43 (TARDBP), partial	E.coli
CSB-EP023129HU(A4)	Recombinant Human TAR DNA-binding protein 43 (TARDBP)	E.coli
CSB-EP023129HU2	Recombinant Human TAR DNA-binding protein 43 (TARDBP), partial	E.coli
CSB-EP023129HU(A4)a0	Recombinant Human TAR DNA-binding protein 43 (TARDBP)	E.coli