SH3RF1
SH3RF1，全稱為SH3結構域含環(huán)指蛋白1，是一種含有多個SH3結構域和RING指結構域的蛋白質。該蛋白參與神經元遷移、T細胞激活等細胞過程，并定位于細胞膜下基質中。SH3RF1蛋白在多種組織中表達，包括中樞神經系統(tǒng)和泌尿生殖系統(tǒng)。研究表明，SH3RF1蛋白在某些癌癥中異常表達，與腫瘤的發(fā)生和發(fā)展相關。此外，SH3RF1蛋白還與神經退行性疾病如帕金森病有關，可能通過調控神經元存活和突觸功能發(fā)揮作用。目前，針對SH3RF1蛋白的藥物研發(fā)尚處于起步階段，但已有研究探索其作為潛在藥物靶點的可能性。例如，有研究開發(fā)了一種基于細胞外囊泡介導的SH3RF1蛋白遞送系統(tǒng)，用于靶向降解靶蛋白，這為SH3RF1蛋白相關疾病的治療提供了新的思路。
熱銷產品
SH3RF1 Antibody (CSB-PA773800LA01HU)
驗證數(shù)據
Immunofluorescence staining of Hela cells with CSB-PA773800LA01HU at 1:200, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
SH3RF1 Antibodies
SH3RF1 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA021241GA01HU | SH3RF1 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA773800LA01HU | SH3RF1 Antibody | Human | ELISA, IF |
| CSB-PA773800LB01HU | SH3RF1 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA773800LC01HU | SH3RF1 Antibody, FITC conjugated | Human | |
| CSB-PA773800LD01HU | SH3RF1 Antibody, Biotin conjugated | Human | ELISA |
SH3RF1 Proteins
SH3RF1 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP773800HU CSB-EP773800HU CSB-BP773800HU CSB-MP773800HU CSB-EP773800HU-B |
Recombinant Human E3 ubiquitin-protein ligase SH3RF1 (SH3RF1), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
