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SFRP1

Secreted frizzled-related protein 1 is a protein in humans that is encoded by SFRP1 gene. Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP1 decreases intracellular beta-catenin levels (By similarity). Has antiproliferative effects on vascular cells, in vitro and in vivo, and can induce, in vivo, an angiogenic response. In vascular cell cycle, delays the G1 phase and entry into the S phase (By similarity). In kidney development, inhibits tubule formation and bud growth in metanephroi (By similarity). Inhibits WNT1/WNT4-mediated TCF-dependent transcription.

SFRP1 Antibodies

SFRP1 for Homo sapiens (Human)

SFRP1 Proteins

SFRP1 Proteins for Bos taurus (Bovine)

SFRP1 Proteins for Mus musculus (Mouse)

SFRP1 Proteins for Homo sapiens (Human)

SFRP1 Proteins for Gallus gallus (Chicken)

SFRP1 Proteins for Rattus norvegicus (Rat)

SFRP1 ELISA Kit

SFRP1 ELISA Kit for Homo sapiens (Human)



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