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RUBCN

Run domain Beclin-1-interacting and cysteine-rich domain-containing protein is a protein in humans that is encoded by RUBCN gene. Inhibits PIK3C3 activity; under basal conditions negatively regulates PI3K complex II (PI3KC3-C2) function in autophagy. Negatively regulates endosome maturation and degradative endocytic trafficking and impairs autophagosome maturation process. Can sequester UVRAG from association with a class C Vps complex (possibly the HOPS complex) and negatively regulates Rab7 activation

RUBCN Antibodies

RUBCN for Homo sapiens (Human)

RUBCN Proteins

RUBCN Proteins for Mus musculus (Mouse)

RUBCN Proteins for Homo sapiens (Human)



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