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PRNP

PRNP,即朊蛋白前體,別名AltPrP、ASCR、CD230。它是一種由PRNP基因編碼的蛋白質,廣泛存在于人體多種組織中,尤其在中樞神經系統。PRNP的作用機制涉及其正常形式PrPC參與細胞黏附和信號傳導,而當PrPC錯誤折疊成PrPSc時,會形成淀粉樣纖維并積累,引發神經細胞損傷。PRNP的生物學意義在于其與多種神經退行性疾病密切相關,尤其是朊病毒病,如克雅氏病等,這些疾病由PrPSc的異常聚集導致,目前尚缺乏有效治療手段,使PRNP成為神經科學研究的重要靶點。

熱銷產品

PRNP Antibody (CSB-PA018739LA01HU)

驗證數據

CSB-PA018739LA01HU

Immunohistochemistry of paraffin-embedded human pancreatic cancer using CSB-PA018739LA01HU at dilution of 1:100

CSB-PA018739LA01HU

Immunofluorescent analysis of PC-3 cells using CSB-PA018739LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

Human Major prion protein(PRNP) ELISA kit (CSB-EL018739HU)

驗證數據

CSB-EL018739HU 標準曲線

貨號:CSB-EL018739HU

規格:96T/48T

靈敏度:0.078 ng/mL

檢測范圍:0.312 ng/mL-20 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

PRNP Antibodies

PRNP for Homo sapiens (Human)

PRNP ELISA Kit

PRNP ELISA Kit for Homo sapiens (Human)



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