MMP14

MMP14，即基質(zhì)金屬蛋白酶14，別名MT1-MMP。它由人類MMP14基因編碼，位于染色體12上。MMP14是一種膜型基質(zhì)金屬蛋白酶，主要在細(xì)胞表面發(fā)揮作用，通過(guò)其催化活性區(qū)含有的鋅離子結(jié)合位點(diǎn)，對(duì)酶催化作用的發(fā)揮至關(guān)重要。MMP14的作用機(jī)制包括激活其他MMPs（如MMP2），參與細(xì)胞外基質(zhì)的重塑，影響腫瘤的侵襲和轉(zhuǎn)移。MMP14參與組織發(fā)育、生殖、組織重塑等正常生理過(guò)程，同時(shí)在疾病過(guò)程中如關(guān)節(jié)炎、腫瘤轉(zhuǎn)移中發(fā)揮作用。MMP14的表達(dá)水平在多種腫瘤中上調(diào)，與腫瘤的預(yù)后密切相關(guān)，如在胰腺癌、肝癌等腫瘤中高表達(dá)與不良預(yù)后相關(guān)。此外，MMP14還參與調(diào)節(jié)免疫反應(yīng)和炎癥過(guò)程。

熱銷產(chǎn)品

Recombinant Human Matrix metalloproteinase-14 (MMP14) (CSB-EP014661HU)

驗(yàn)證數(shù)據(jù)

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of CSB-EP014661HU could indicate that this peptide derived from E.coli-expressed Homo sapiens (Human) MMP14.

MMP14 Antibody (CSB-PA014661ESR1HU)

驗(yàn)證數(shù)據(jù)

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA014661ESR1HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA014661ESR1HU at dilution of 1:100

MMP14 Antibody

MMP14 Protein

MMP14 ELISA Kit

MMP14 Antibodies

MMP14 for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA014661GA01HU	MMP14 Antibody	Human,Mouse,Rat,Zebrafish	ELISA,WB
CSB-PA12389D0Rb	MMP14 Antibody, Biotin conjugated	Human	ELISA
CSB-PA12389A0Rb	MMP14 Antibody	Human	ELISA, IHC
CSB-PA014661ESR1HU	MMP14 Antibody	Human	ELISA, IHC
CSB-PA897896	MMP14 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA000050	Cleaved-MMP14 (Y112) Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA010212	MMP14 Antibody	Human,Mouse,Rat	WB, IHC, ELISA
CSB-PA971298	MMP14 Antibody	Human,Mouse,Rat	ELISA,IHC
CSB-PA553918	MMP14 Antibody	Human,Mouse,Rat	ELISA,IHC

MMP14 Proteins

MMP14 Proteins for Homo sapiens (Human)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP014661HU CSB-BP014661HU CSB-MP014661HU CSB-EP014661HU-B	Recombinant Human Matrix metalloproteinase-14 (MMP14), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP014661HU	Recombinant Human Matrix metalloproteinase-14 (MMP14)	E.coli
CSB-CF014661HU	Recombinant Human Matrix metalloproteinase-14 (MMP14)	in vitro E.coli expression system

MMP14 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP014661MO1 CSB-BP014661MO1 CSB-MP014661MO1 CSB-EP014661MO1-B	Recombinant Mouse Matrix metalloproteinase-14 (Mmp14), partial	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-CF014661MO	Recombinant Mouse Matrix metalloproteinase-14 (Mmp14)	in vitro E.coli expression system

MMP14 Proteins for Rattus norvegicus (Rat)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP608834RA CSB-EP608834RA CSB-BP608834RA CSB-MP608834RA CSB-EP608834RA-B	Recombinant Rat Matrix metalloproteinase-14 (Mmp14), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MMP14 Proteins for Pongo abelii (Sumatran orangutan)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP725453PYX CSB-EP725453PYX CSB-BP725453PYX CSB-MP725453PYX CSB-EP725453PYX-B	Recombinant Pongo abelii Matrix metalloproteinase-14 (MMP14), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MMP14 Proteins for Oryctolagus cuniculus (Rabbit)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP839160RB CSB-EP839160RB CSB-BP839160RB CSB-MP839160RB CSB-EP839160RB-B	Recombinant Rabbit Matrix metalloproteinase-14 (MMP14), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MMP14 Proteins for Bos taurus (Bovine)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP884395BO CSB-EP884395BO CSB-BP884395BO CSB-MP884395BO CSB-EP884395BO-B	Recombinant Bovine Matrix metalloproteinase-14 (MMP14), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

MMP14 Proteins for Sus scrofa (Pig)

產(chǎn)品貨號(hào)	產(chǎn)品名稱	來(lái)源
CSB-YP896435PI CSB-EP896435PI CSB-BP896435PI CSB-MP896435PI CSB-EP896435PI-B	Recombinant Pig Matrix metalloproteinase-14 (MMP14), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli