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MME

MME,全名為膜金屬內(nèi)肽酶(membrane metalloendopeptidase),也被稱為中性內(nèi)肽酶、腦啡肽酶、神經(jīng)肽酶等。MME蛋白在細胞表面表達,主要功能是降解多肽,包括阿片肽、緩激肽、P物質(zhì)和神經(jīng)降壓素肽等。它在神經(jīng)遞質(zhì)和激素的降解中起關(guān)鍵作用,與多種生理過程相關(guān)。MME蛋白與阿爾茨海默病、多發(fā)性硬化癥、癌癥等多種疾病有關(guān),因此成為藥物研發(fā)的熱點靶點。目前,針對MME蛋白的藥物研發(fā)主要集中在開發(fā)能夠抑制其活性的藥物,以治療相關(guān)疾病。

熱銷產(chǎn)品

Recombinant Human Neprilysin (MME), partial (CSB-YP014653HU)

驗證數(shù)據(jù)

CSB-YP014653HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-YP014653HU

Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP014653HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) MME.

CSB-YP014653HU

Based on the SEQUEST from database of Yeast host and target protein, the LC-MS/MS Analysis result of CSB-YP014653HU could indicate that this peptide derived from Yeast-expressed Homo sapiens (Human) MME.

MME Recombinant Monoclonal Antibody (CSB-RA940661A0HU)

驗證數(shù)據(jù)

CSB-RA940661A0HU

Western Blot
Positive WB detected in: U251 whole cell lysate
All lanes: MME antibody at 1:1500
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 86 kDa
Observed band size: 100 kDa

MME Antibodies

MME for Homo sapiens (Human)

MME for H, M, R

MME Proteins

MME Proteins for Sus scrofa (Pig)

MME Proteins for Homo sapiens (Human)

MME Proteins for Oryctolagus cuniculus (Rabbit)

MME Proteins for Rattus norvegicus (Rat)

MME Proteins for Pongo abelii (Sumatran orangutan)

MME Proteins for Mus musculus (Mouse)

MME ELISA Kit

MME ELISA Kit for Mus musculus (Mouse)

MME ELISA Kit for Rattus norvegicus (Rat)

MME ELISA Kit for Homo sapiens (Human)



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