KLF4

KLF4。即Krüppel樣因子4，別名GKLF、epithelial zinc finger protein EZF等。它是一種轉(zhuǎn)錄因子，主要在結(jié)腸癌、胃癌等多種癌癥的腫瘤組織中表達(dá)，并在細(xì)胞增殖、分化、胚胎發(fā)育等重要生命過程中發(fā)揮作用。KLF4的作用機(jī)制涉及通過與下游基因啟動子區(qū)的結(jié)合元件相結(jié)合，直接調(diào)控下游基因的轉(zhuǎn)錄。KLF4具有抑癌和促癌的雙重調(diào)節(jié)作用，在腫瘤發(fā)生、血管重構(gòu)等生理病理過程中起到重要作用。此外，KLF4是體細(xì)胞重編程為誘導(dǎo)多能干細(xì)胞(iPS細(xì)胞)的重要誘導(dǎo)因子之一，對于臨床醫(yī)學(xué)上基因治療技術(shù)的應(yīng)用具有潛在的研究價(jià)值。

熱銷產(chǎn)品

KLF4 Antibody (CSB-PA012394DSR2HU)

驗(yàn)證數(shù)據(jù)

Western blot
All lanes: Krueppel-like factor 4 antibody at 5μg/ml + 293T whole cell lysate
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 55, 52, 46, 13, 7 kDa
Observed band size: 55 kDa

Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA012394DSR2HU at dilution of 1:100

Immunohistochemistry of paraffin-embedded human colon tissue using CSB-PA012394DSR2HU at dilution of 1:100

Human Krueppel-like factor 4(KLF4) ELISA kit (CSB-EL012394HU)

驗(yàn)證數(shù)據(jù)

貨號：CSB-EL012394HU

規(guī)格：96T/48T

靈敏度：4.6 pg/mL

檢測范圍：18.75 pg/mL-1200 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

KLF4 Antibody

KLF4 Protein

KLF4 ELISA Kit

KLF4 Antibodies

KLF4 for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	種屬反應(yīng)性	應(yīng)用類型
CSB-PA012394GA01HU	KLF4 Antibody	Human,Mouse,Rat	ELISA,WB,IF
CSB-PA012394DSR2HU	KLF4 Antibody	Human	ELISA, WB, IHC
CSB-RA194949A0HU	KLF4 Recombinant Monoclonal Antibody	Human	ELISA, WB, IHC, IF, IP

KLF4 Proteins

KLF4 Proteins for Homo sapiens (Human)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP012394HU CSB-EP012394HU CSB-BP012394HU CSB-MP012394HU CSB-EP012394HU-B	Recombinant Human Krueppel-like factor 4 (KLF4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

KLF4 Proteins for Mus musculus (Mouse)

產(chǎn)品貨號	產(chǎn)品名稱	來源
CSB-YP730657MO CSB-EP730657MO CSB-BP730657MO CSB-MP730657MO CSB-EP730657MO-B	Recombinant Mouse Krueppel-like factor 4 (Klf4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli