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IL21

IL21,即白細胞介素-21,是一種由免疫細胞如CD4+T細胞、NK細胞等分泌的細胞因子。它通過結合特異性受體IL-21R,激活JAK/STAT信號通路,調控免疫細胞的增殖、分化和功能。IL21在抗腫瘤免疫中尤為關鍵,能增強T細胞和NK細胞的抗腫瘤活性,促進B細胞生成特異性抗體,從而強化體液免疫。此外,它在自身免疫性疾病中也發揮重要作用,其表達異常可能引發自身免疫反應。

熱銷產品

Recombinant Human Interleukin-21 (IL21) (Active) (CSB-MP872537HU)

驗證數據

CSB-MP872537HU

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP872537HU

Activity
Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis IL21R (CSB-MP7140MOV) at 2 μg/ml can bind Human IL21. The EC50 is 15.01-19.43 ng/mL.

CSB-MP872537HU

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human IL21R (CSB-MP862061HU) at 2 μg/ml can bind Human IL21. The EC50 is 16.65-19.49 ng/mL.

CSB-MP872537HU

Activity
Human IL21 captured on Protein A Chip can bind Recombinant Macaca fascicularis IL21R (CSB-MP7140MOV) with an affinity constant of 1.31 nM as detected by MetaSPR Assay (WeSPRTM 200).

CSB-MP872537HU

Activity
Human IL21 captured on Protein A Chip can bind Recombinant Human IL21R (CSB-MP862061HU) with an affinity constant of 1.87 nM as detected by MetaSPR Assay (WeSPRTM 200).

IL21 Antibody (CSB-PA872537ESR1HU)

驗證數據

CSB-PA872537ESR1HU

Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA872537ESR1HU at dilution of 1:100

CSB-PA872537ESR1HU

Immunohistochemistry of paraffin-embedded human spleen tissue using CSB-PA872537ESR1HU at dilution of 1:100

Human Interleukin 21,IL-21 ELISA Kit (CSB-E11707h)

驗證數據

CSB-E11707h 標準曲線

貨號:CSB-E11707h

規格:96T/48T

靈敏度:0.78 pg/mL

檢測范圍:3.12 pg/mL-200 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

IL21 Antibodies

IL21 for Homo sapiens (Human)

IL21 Proteins

IL21 Proteins for Rattus norvegicus (Rat)

IL21 Proteins for Sus scrofa (Pig)

IL21 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)

IL21 Proteins for Bos taurus (Bovine)

IL21 Proteins for Peromyscus maniculatus (North American deer mouse)

IL21 Proteins for Homo sapiens (Human)

IL21 Proteins for Mus musculus (Mouse)

IL21 ELISA Kit

IL21 ELISA Kit for Homo sapiens (Human)

IL21 ELISA Kit for Mus musculus (Mouse)

IL21 ELISA Kit for Rattus norvegicus (Rat)



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