HOMER3
HOMER3，全稱為Homer scaffolding protein 3，是一種突觸后密度支架蛋白，參與多種生物學(xué)功能。該蛋白具有多種別名，如VESL3和HOMER-3。HOMER3蛋白在神經(jīng)元信號傳導(dǎo)、T細(xì)胞激活和淀粉樣蛋白β肽的運(yùn)輸中發(fā)揮重要作用。研究表明，HOMER3蛋白與I組代謝型谷氨酸受體、肌醇1,4,5-三磷酸受體和淀粉樣蛋白前體蛋白等多種蛋白質(zhì)結(jié)合。HOMER3蛋白的表達(dá)廣泛分布于脾臟、腎臟和其他組織中。在疾病方面，HOMER3蛋白與多種疾病相關(guān)，包括小腦性共濟(jì)失調(diào)、阿爾茨海默病和癌癥等。目前，針對HOMER3蛋白的藥物研發(fā)尚處于早期階段，但已有研究表明，靶向HOMER3蛋白的藥物可能成為治療癌癥和神經(jīng)退行性疾病的新策略。
熱銷產(chǎn)品
HOMER3 Antibody (CSB-PA878880LA01HU)
驗(yàn)證數(shù)據(jù)
Western Blot
Positive WB detected in: Mouse brain tissue
All lanes: HOMER3 antibody at 2.7μg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 40, 17, 14, 36 kDa
Observed band size: 40 kDa
Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA878880LA01HU at dilution of 1:100
HOMER3 Antibodies
HOMER3 for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA010638GA01HU | HOMER3 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA878880LA01HU | HOMER3 Antibody | Human, Mouse | ELISA, WB, IHC |
| CSB-PA878880LD01HU | HOMER3 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA878880LC01HU | HOMER3 Antibody, FITC conjugated | Human | |
| CSB-PA878880LB01HU | HOMER3 Antibody, HRP conjugated | Human | ELISA |
HOMER3 Proteins
HOMER3 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP860797MO CSB-EP860797MO CSB-BP860797MO CSB-MP860797MO CSB-EP860797MO-B |
Recombinant Mouse Homer protein homolog 3 (Homer3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
HOMER3 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP878880HU CSB-EP878880HU CSB-BP878880HU CSB-MP878880HU CSB-EP878880HU-B |
Recombinant Human Homer protein homolog 3 (HOMER3) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
