FGF8
成纖維細(xì)胞生長(zhǎng)因子8（FGF8），別稱AIGF和HBGF-8。FGF8在細(xì)胞生長(zhǎng)、發(fā)育和分化中發(fā)揮著重要的調(diào)節(jié)作用，參與多種生理病理過(guò)程。
FGF8與多種疾病的發(fā)生發(fā)展密切相關(guān)。研究表明，F(xiàn)GF8的表達(dá)異常與骨骼發(fā)育畸形、骨關(guān)節(jié)炎、大骨節(jié)病、顱縫早閉和腭裂等疾病有關(guān)。FGF8在骨骼發(fā)育中發(fā)揮著重要作用，其表達(dá)水平的變化會(huì)影響骨骼的生長(zhǎng)和礦化。在骨關(guān)節(jié)炎中，F(xiàn)GF8可能作為促分解因子發(fā)揮作用，促進(jìn)軟骨基質(zhì)降解和關(guān)節(jié)損傷。大骨節(jié)病是一種地方性骨關(guān)節(jié)病，患者關(guān)節(jié)軟骨中FGF8的表達(dá)明顯增多。顱縫早閉是一種發(fā)育畸形，F(xiàn)GF8信號(hào)通路中的突變是導(dǎo)致顱縫過(guò)早融合的主要原因之一。腭裂是一種常見的先天性發(fā)育畸形，F(xiàn)GF8基因的突變會(huì)導(dǎo)致腭裂的發(fā)生。
針對(duì)FGF8相關(guān)疾病，研究人員正在探索多種治療策略。例如，開發(fā)針對(duì)FGF8受體的抑制劑，以降低FGF8信號(hào)通路的活性。此外，研究人員也在探索FGF8基因治療的可能性，以糾正FGF8表達(dá)異常導(dǎo)致的疾病。目前，F(xiàn)GF8相關(guān)疾病的治療仍處于研究階段，未來(lái)還需要更多的臨床研究來(lái)驗(yàn)證其有效性和安全性。
熱銷產(chǎn)品
Recombinant Human Fibroblast growth factor 8 (FGF8), partial (CSB-EP008637HU1)
驗(yàn)證數(shù)據(jù)
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
FGF8 Antibody (CSB-PA008637LA01HU)
驗(yàn)證數(shù)據(jù)
Immunohistochemistry of paraffin-embedded human ovarian cancer using CSB-PA008637LA01HU at dilution of 1:100
Human Fibroblast Growth Factor 8(FGF8) ELISA Kit (CSB-E15861h)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-E15861h
規(guī)格：96T/48T
靈敏度：3.9 pg/mL
檢測(cè)范圍：15.6 pg/mL-1000 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
FGF8 Antibodies
FGF8 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA005770 | FGF8 Antibody | Human,Mouse,Rat | WB, ELISA |
| CSB-PA123716 | FGF8 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA008637LA01HU | FGF8 Antibody | Human | ELISA, IHC |
| CSB-PA008637LB01HU | FGF8 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA008637LC01HU | FGF8 Antibody, FITC conjugated | Human | |
| CSB-PA008637LD01HU | FGF8 Antibody, Biotin conjugated | Human | ELISA |
FGF8 Proteins
FGF8 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP008637MO CSB-BP008637MO CSB-MP008637MO CSB-EP008637MO-B |
Recombinant Mouse Fibroblast growth factor 8 (Fgf8) | Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FGF8 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP008637HU CSB-EP008637HU CSB-BP008637HU CSB-MP008637HU CSB-EP008637HU-B |
Recombinant Human Fibroblast growth factor 8 (FGF8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP004031HU | Recombinant Human Fibroblast growth factor 8 (FGF8) (Active) | E.coli |
| CSB-AP004041HU | Recombinant Human Fibroblast growth factor 8 (FGF8), partial (Active) | E.coli |
| CSB-EP008637HU1 | Recombinant Human Fibroblast growth factor 8 (FGF8), partial | E.coli |
FGF8 Proteins for Canis familiaris (Dog) (Canis lupus familiaris)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP008637DO CSB-EP008637DO CSB-BP008637DO CSB-MP008637DO CSB-EP008637DO-B |
Recombinant Dog Fibroblast growth factor 8 (FGF8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FGF8 Proteins for Gallus gallus (Chicken)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP845867CH CSB-EP845867CH CSB-BP845867CH CSB-MP845867CH CSB-EP845867CH-B |
Recombinant Chicken Fibroblast growth factor 8 (FGF8) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
FGF8 ELISA Kit
FGF8 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E15861h | Human Fibroblast Growth Factor 8(FGF8) ELISA Kit | serum, plasma, tissue homogenates, cell lysates | 3.9 pg/mL |
