CTF1
CTF1，全名為Cardiotrophin-1，別名包括CARDIOPHIN 1、CT-1、CTF1、CARDIOTROPHIN 1、CT1。該蛋白與心臟發(fā)育和功能密切相關(guān)，在心肌細(xì)胞肥大過(guò)程中發(fā)揮關(guān)鍵作用。研究表明，CTF1通過(guò)與ILST/gp130受體的結(jié)合和激活介導(dǎo)心肌細(xì)胞肥大，對(duì)心肌發(fā)育和擴(kuò)大的影響。此外，CTF1還參與多種生理和病理過(guò)程，如細(xì)胞增殖、分化、凋亡等，并在某些疾病的發(fā)生發(fā)展中發(fā)揮作用。
CTF1相關(guān)疾病主要包括心臟疾病，如心肌肥大、心力衰竭等。此外，CTF1還與一些罕見(jiàn)病和腫瘤相關(guān)，如神經(jīng)纖維瘤病、白血病等。針對(duì)CTF1蛋白的藥物研發(fā)正在積極推進(jìn)中，包括小分子抑制劑、抗體藥物偶聯(lián)物（ADC）等。其中，一些藥物已進(jìn)入臨床試驗(yàn)階段，顯示出良好的療效和安全性。未來(lái)，CTF1蛋白有望成為治療心臟疾病和腫瘤的重要靶點(diǎn)。
熱銷產(chǎn)品
CTF1 Antibody (CSB-PA621965LA01HU)
驗(yàn)證數(shù)據(jù)
IHC image of CSB-PA621965LA01HU diluted at 1:100 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Human cardiotrophln 1,CT-1 ELISA Kit (CSB-E08454h)
驗(yàn)證數(shù)據(jù)
貨號(hào)：CSB-E08454h
規(guī)格：96T/48T
靈敏度：1.95 pg/mL
檢測(cè)范圍：7.8 pg/mL-500 pg/mL
These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
CTF1 Antibodies
CTF1 for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA001216 | CTF1 Antibody | Human,Mouse,Rat | WB, IHC, ELISA |
| CSB-PA765237 | CTF1 Antibody | Human,Mouse,Rat | WB,ELISA |
| CSB-PA621965LA01HU | CTF1 Antibody | Human | ELISA, IHC |
CTF1 Proteins
CTF1 Proteins for Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP529804SXV CSB-EP529804SXV CSB-BP529804SXV CSB-MP529804SXV CSB-EP529804SXV-B |
Recombinant Schizosaccharomyces pombe Cleavage and termination factor 1 (ctf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CTF1 Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP621965HU CSB-EP621965HU CSB-BP621965HU CSB-MP621965HU CSB-EP621965HU-B |
Recombinant Human Cardiotrophin-1 (CTF1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
CTF1 Proteins for Rattus norvegicus (Rat)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP726877RA CSB-EP726877RA CSB-BP726877RA CSB-MP726877RA CSB-EP726877RA-B |
Recombinant Rat Cardiotrophin-1 (Ctf1) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
| CSB-AP000211RA | Recombinant Rat Cardiotrophin-1 protein (Ctf1) | E.Coli |
CTF1 Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 來(lái)源 |
|---|---|---|
| CSB-YP733705MO CSB-BP733705MO CSB-EP733705MO-B |
Recombinant Mouse Cardiotrophin-1 (Ctf1) | Yeast Baculovirus In Vivo Biotinylation in E.coli |
| CSB-AP000531MO | Recombinant Mouse Cardiotrophin-1 protein (Ctf1) | E.Coli |
CTF1 ELISA Kit
CTF1 ELISA Kit for Homo sapiens (Human)
| 產(chǎn)品貨號(hào) | 產(chǎn)品名稱 | 樣本類型 | 靈敏度 |
|---|---|---|---|
| CSB-E08454h | Human cardiotrophln 1,CT-1 ELISA Kit | serum, plasma, cell culture supernates, tissue homogenates | 1.95 pg/mL |
