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CLDN9

CLDN9,全稱為Claudin-9,是一種緊密連接蛋白,常見別名為DFNB116。它在細胞間形成緊密連接,維持細胞極性和信號傳導。CLDN9在丙型肝炎病毒的進入過程中發揮輔助作用,與聽覺器官中感覺細胞的保護有關,基因缺陷可能與耳聾相關。此外,CLDN9在腫瘤調控中扮演重要角色,其高表達與食管腺癌糖酵解相關。目前,針對CLDN9的藥物研發正在推進,有望成為治療癌癥和其他疾病的潛在靶點。

熱銷產品

Recombinant Human Claudin-9 (CLDN9), partial-Detergent (Active) (CSB-MP005511HU1-D)

驗證數據

CSB-MP005511HU1-D

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

CSB-MP005511HU1-D

Activity
Measured by its binding ability in a functional ELISA. Immobilized Human CLDN9 at 2 μg/ml on an Nickel Coated plate can bind Anti-CLDN6/9 recombinant antibody (CSB-RA005508MA1HU). The EC50 is 2.812-3.524 ng/mL.

CLDN9 Antibodies

CLDN9 for Homo sapiens (Human)

CLDN9 Proteins

CLDN9 Proteins for Homo sapiens (Human)



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