欧美最新另类人妖I国产成人av一区二区三区在线观看I九九热精品视频在线观看I国产精品日韩在线I激情av五月婷婷I日韩精品免费

Your Good Partner in Biology Research

ABAT

ABAT,全稱為γ-氨基丁酸轉氨酶,也常被簡稱為GABA-T。它是維持神經系統穩定的重要分子,主要參與抑制性神經遞質γ-氨基丁酸的代謝過程,通過促進該遞質的分解來調控其在體內的濃度平衡。當ABAT功能異常時,γ-氨基丁酸的代謝會出現紊亂,可能引發一系列神經系統疾病,其中較為典型的是遺傳性GABA轉氨酶缺乏癥,患者多在嬰幼兒階段發病,表現為頻繁癲癇發作、智力發育遲緩等癥狀。在臨床治療領域,針對該蛋白的藥物已得到應用,比如氨己烯酸,它能降低這個蛋白的活性,從而提升體內γ-氨基丁酸的水平,幫助緩解癲癇發作,目前已成為嬰兒痙攣癥等難治性癲癇的重要治療藥物之一。

熱銷產品

Recombinant Human 4-aminobutyrate aminotransferase, mitochondrial (ABAT) (CSB-EP001032HUe0)

驗證數據

CSB-EP001032HUe0

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ABAT Recombinant Monoclonal Antibody (CSB-RA242969A0HU)

驗證數據

CSB-RA242969A0HU

IHC image of CSB-RA242969A0HU diluted at 1:100 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4℃ overnight. The primary is detected by a Goat anti-rabbit IgG polymer labeled by HRP and visualized using 0.05% DAB.

ABAT Antibody (CSB-PA001032ESR1HU)

驗證數據

CSB-PA001032ESR1HU

Western blot
All lanes: 4-aminobutyrate aminotransferase, mitochondrial antibody at 10μg/ml
Lane 1: Rat liver tissue
Lane 2: Mouse pancreatic tissue
Lane 3: Mouse kidney tissue
Secondary
Goat polyclonal to rabbit IgG at 1/10000 dilution
Predicted band size: 56 kDa
Observed band size: 56 kDa

CSB-PA001032ESR1HU

Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA001032ESR1HU at dilution of 1:100

CSB-PA001032ESR1HU

Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA001032ESR1HU at dilution of 1:100

ABAT Antibodies

ABAT for Homo sapiens (Human)

ABAT Proteins

ABAT Proteins for Homo sapiens (Human)



×