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  4. PLD4 (SBI-3150 Biosimilar) Recombinant Monoclonal Antibody

PLD4 (SBI-3150 Biosimilar) Recombinant Monoclonal Antibody

  • 貨號：
    CSB-RA839298MB1HU
  • 規(guī)格：
    ￥83486
  • 其他：

產品詳情

  • 產品描述：
    PLD4 (SBI-3150 Biosimilar Antibody)重組單克隆抗體是一款專為科研用途開發(fā)的生物試劑，旨在為生命科學研究提供高質量的分子工具。該產品通過基因工程技術制備，具有高特異性和批次穩(wěn)定性，適用于多種實驗場景。 作為重組單克隆抗體，PLD4 (SBI-3150) 采用先進的CHO細胞表達系統(tǒng)生產，經過嚴格的純化工藝，確保極低的內毒素水平和高純度。其靶向PLD4蛋白的特異性結合能力，為研究該蛋白在生理和病理過程中的功能提供了可靠支持，可應用于等常見分子生物學實驗。 該抗體在研發(fā)過程中經過多輪篩選和驗證，確保與靶標蛋白的高親和力和低交叉反應性。其穩(wěn)定的理化性質使其在長期儲存和多次凍融循環(huán)后仍能保持活性，滿足科研實驗對試劑穩(wěn)定性的嚴格要求。此外，產品提供詳細的質量控制報告，包括效價、純度和活性檢測數據，為實驗結果的可重復性和可靠性提供保障。 PLD4 (SBI-3150 Biosimilar Antibody)重組單克隆抗體的應用范圍涵蓋基礎醫(yī)學研究、蛋白質功能分析、信號通路探索等領域，為科研人員深入理解PLD4相關的分子機制和疾病模型研究提供有力支持。其標準化的生產流程和嚴格的質量控制體系，使其成為生命科學研究中值得信賴的實驗工具。
  • Uniprot No.：
  • 基因名：
  • 別名：
    AK1910 research-grade biosimilar; AK 1910 research-grade biosimilar; SBI3150 research-grade biosimilar; SBI 3150 research-grade biosimilar ;PLD4 antibody; C14orf175 antibody; UNQ2488/PRO5775 antibody; 5'-3' exonuclease PLD4 antibody; EC 3.1.16.1 antibody; (S,S-bis(monoacylglycerophosphate synthase PLD4 antibody; EC 3.1.4.- antibody; Phospholipase D family member 4 antibody; Phospholipase D4 antibody
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human PLD4 protein
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Monoclonal
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    0.01M PBS，pH7.4
  • 產品提供形式：
    Liquid
  • 應用說明：
    Validation Status
    Application-specific performance (e.g., in flow cytometry, ELISA, IHC or other assay formats) has not yet been experimentally verified by CUSABIO. Users are advised to determine the optimal working conditions empirically in their own assay systems.
    Guaranteed Quality
    ① Antibody purity?> 95% tested by SDS-PAGE.
    ② Endotoxin level < 0.1EU/ug tested by LAL method.
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    3-4 weeks
  • 用途：
    It is a non-therapeutic biosimilar antibody, owning the same variable region from the corresponding approved therapeutic antibody. In conclusion, it is a research-grade biosimilar antibody and expressed in mammalian cell, which can be directly used as positive controls in drug discovery or used for rapid verification of the biological functions of target protein.

產品評價

靶點詳情

  • 功能：
    5'->3' DNA exonuclease which digests single-stranded DNA (ssDNA). Regulates inflammatory cytokine responses via the degradation of nucleic acids, by reducing the concentration of ssDNA able to stimulate TLR9, a nucleotide-sensing receptor. Involved in phagocytosis of activated microglia.
  • 基因功能參考文獻：
    1. PLD4 expression in colon cancer tissues PMID: 27840999
    2. We determined that PLD4 is a novel susceptibility gene for sysetmic sclerosis in Japanese, thus confirming the involvement of PLD4 in autoimmunity. PMID: 23124809
  • 亞細胞定位：
    Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass type II membrane protein. Nucleus. Early endosome. Cytoplasmic vesicle, phagosome.
  • 蛋白家族：
    Phospholipase D family
  • 數據庫鏈接：

    HGNC: 23792

    KEGG: hsa:122618

    STRING: 9606.ENSP00000376372

    UniGene: Hs.407101



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