Recombinant Xenopus tropicalis E3 ubiquitin-protein ligase arkadia (rnf111), partial

中文名稱：

熱帶爪蟾rnf111重組蛋白
貨號：

CSB-YP605739XBF
規(guī)格：
來源：

Yeast
其他：

中文名稱：

熱帶爪蟾rnf111重組蛋白
貨號：

CSB-EP605739XBF
規(guī)格：
來源：

E.coli
其他：

中文名稱：

熱帶爪蟾rnf111重組蛋白
貨號：

CSB-EP605739XBF-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

熱帶爪蟾rnf111重組蛋白
貨號：

CSB-BP605739XBF
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

熱帶爪蟾rnf111重組蛋白
貨號：

CSB-MP605739XBF
規(guī)格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

rnf111
Uniprot No.：

Q0V9R0
別名：

rnf111; E3 ubiquitin-protein ligase arkadia; EC 2.3.2.27; RING finger protein 111; RING-type E3 ubiquitin transferase arkadia
種屬：

Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

E3 ubiquitin-protein ligase required for mesoderm patterning during embryonic development. Acts as an enhancer of the transcriptional responses of the smad2/smad3 effectors, which are activated downstream of BMP. Acts by mediating ubiquitination and degradation of SMAD inhibitors such as smad7, inducing their proteasomal degradation and thereby enhancing the transcriptional activity of TGF-beta and BMP. Specifically binds polysumoylated chains via SUMO interaction motifs (SIMs) and mediates ubiquitination of sumoylated substrates. The regulation of the BMP-SMAD signaling is however independent of sumoylation and is not dependent of SUMO interaction motifs (SIMs).
亞細胞定位：

Nucleus. Cytoplasm. Nucleus, PML body.
蛋白家族：

Arkadia family
數據庫鏈接：

KEGG: xtr:780266

STRING: 8364.ENSXETP00000023715

UniGene: Str.43076