Recombinant Xenopus laevis Transcription factor Sox-17-alpha-A (sox17a-a)

中文名稱：

有爪蟾蜍sox17a-a重組蛋白
貨號：

CSB-YP667291XBE
規格：
來源：

Yeast
其他：

中文名稱：

有爪蟾蜍sox17a-a重組蛋白
貨號：

CSB-EP667291XBE
規格：
來源：

E.coli
其他：

中文名稱：

有爪蟾蜍sox17a-a重組蛋白
貨號：

CSB-EP667291XBE-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

有爪蟾蜍sox17a-a重組蛋白
貨號：

CSB-BP667291XBE
規格：
來源：

Baculovirus
其他：

中文名稱：

有爪蟾蜍sox17a-a重組蛋白
貨號：

CSB-MP667291XBE
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

sox17a-a
Uniprot No.：

Q3KQ35
別名：

sox17a-a; sox17a; sox17a1; Transcription factor Sox-17-alpha-A; Xsox17alpha; xSox17alpha1
種屬：

Xenopus laevis (African clawed frog)
蛋白長度：

full length protein
表達區域：

1-380
氨基酸序列

MSSPDGGYAS DDQNQGKCSV PIMMTGLGQC QWAEPMTSLG EGKLKSDAGS ANSRSKAEAR IRRPMNAFMV WAKDERKRLA QQNPDLHNAE LSKMLGKSWK SLTLAEKRPF VEEAERLRVQ HMQDHPNYKY RPRRRKQVKR MKRAENGFMH MAEAQESAVL GADGRMCLEN FSLGYHEQTY PHGQVPQSSH YREPQAVAPH YDGYSLPTPE SSPLDLAEAD PVFFTSPAQD ECQMMPYSYN GSYPHQQNSM LVRQMPQTEQ MGQVSPVQGM MACQSSPHMY YGQMYLPGSA RHHQLHQAGQ PSPPPEAQQM GRADHIQPAD MLAEVDRTEF EQYLSYVAKS DLGMHYHAQE SVVPTADNGP ISSVLSDAST AVYYCNYPSA
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Transcriptional activator. Binds to the DNA sequence 5'-AACAAT-3'. All of the sox17 proteins are required for embryonic endoderm development and gastrulation movements, and show some redundancy in function. In addition, the sox17 proteins have distinct but overlapping roles in later gut development. Acts downstream of vegt-signaling in endoderm differentiation to induce a range of endodermal genes both directly (including endodermin and dhh/chh) and indirectly. Also represses wnt-responsive genes to inhibit wnt/beta-catenin signaling.
基因功能參考文獻：
1. two regions co-operate in regulating the early endodermal expression of the Xsox17alpha(1) gene PMID: 17719026
亞細胞定位：

Nucleus.
組織特異性：

In early gastrulae, expressed in the vegetal but not animal hemisphere. The vegetal region is fated to become endoderm, and endodermal expression continues throughout gastrulation and neurulation. At tailbud stages, expression is down-regulated and become
數據庫鏈接：

KEGG: xla:397966

UniGene: Xl.3831