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中文名稱：Recombinant Tityus zulianus Beta-toxin Tz1
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品名簡稱：Recombinant Tityus zulianus Beta-toxin Tz1 protein
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貨號：CSB-EP649921TAAJ
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說明書：
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規格：￥2328
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圖片：
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(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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其他：
產品詳情
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純度：Greater than 85% as determined by SDS-PAGE.
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基因名：N/A
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Uniprot No.：
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別名：Beta-toxin Tz1; PT-beta NaTx14.1
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種屬：Tityus zulianus(Venezuelan scorpion)
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蛋白長度：Full Length of Mature Protein
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來源：E.coli
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分子量：14.8 kDa
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表達區域：21-84aa
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氨基酸序列KDGYLVGNDGCKYSCFTRPGTYCANECSRVKGKDGYCYAWMACYCYSMPNWVKTWDRATNRCGR
Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering. -
蛋白標簽：N-terminal 10xHis-tagged and C-terminal Myc-tagged
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產品提供形式：Liquid or Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
緩沖液：Tris-based buffer,50% glycerol
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儲存條件：Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保質期：The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期：3-7 business days
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注意事項：Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Datasheet & COA：Please contact us to get it.
產品評價
相關產品
靶點詳情
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功能：Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repetitive firing. Strongly affects skeletal muscle channels Nav1.4/SCN4A, poorly affects the neuronal channels Nav1.6/SCN8A and Nav1.2/SCN2A. Induces spastic paralysis of rear limbs, increased salivation, apnea, tachycardia and increased perspiration.
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亞細胞定位：Secreted.
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蛋白家族：Long (4 C-C) scorpion toxin superfamily, Sodium channel inhibitor family, Beta subfamily
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組織特異性：Expressed by the venom gland.
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