Recombinant Thermus thermophilus Chaperone protein ClpB (clpB), partial

中文名稱：

Recombinant Thermus thermophilus Chaperone protein ClpB(clpB) ,partial
貨號：

CSB-YP882633TNT
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Thermus thermophilus Chaperone protein ClpB(clpB) ,partial
貨號：

CSB-EP882633TNT
規格：
來源：

E.coli
其他：

中文名稱：

Recombinant Thermus thermophilus Chaperone protein ClpB(clpB) ,partial
貨號：

CSB-EP882633TNT-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Thermus thermophilus Chaperone protein ClpB(clpB) ,partial
貨號：

CSB-BP882633TNT
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Thermus thermophilus Chaperone protein ClpB(clpB) ,partial
貨號：

CSB-MP882633TNT
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

clpB
Uniprot No.：

Q9RA63
別名：

clpB; TTHA1487Chaperone protein ClpB
種屬：

Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE. Acts before DnaK, in the processing of protein aggregates. Protein binding stimulates the ATPase activity; ATP hydrolysis unfolds the denatured protein aggregates, which probably helps expose new hydrophobic binding sites on the surface of ClpB-bound aggregates, contributing to the solubilization and refolding of denatured protein aggregates by DnaK.
基因功能參考文獻：
1. Results indicate the ATP-driven oligomeric-state transitions that enable ClpB to disentangle protein aggregates. PMID: 29858573
2. Data indicate that AAA+ chaperone ClpB cooperatively hydrolyzes ATP, and this cooperativity is crucial for protein disaggregation. PMID: 25713084
3. Data indicate that both arginines couple nucleotide binding to oligomerization and allosterically regulate the ATPase activity of AAA+ chaperone ClpB. PMID: 25253689
亞細胞定位：

Cytoplasm.
蛋白家族：

ClpA/ClpB family
數據庫鏈接：

KEGG: ttj:TTHA1487

STRING: 300852.TTHA1487