Recombinant Thermoplasma volcanium Probable N-glycosylase/DNA lyase (ogg)

中文名稱：

Recombinant Thermoplasma volcanium Probable N-glycosylase/DNA lyase(ogg)
貨號：

CSB-YP857124TDL
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Thermoplasma volcanium Probable N-glycosylase/DNA lyase(ogg)
貨號：

CSB-EP857124TDL
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Thermoplasma volcanium Probable N-glycosylase/DNA lyase(ogg)
貨號：

CSB-EP857124TDL-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Thermoplasma volcanium Probable N-glycosylase/DNA lyase(ogg)
貨號：

CSB-BP857124TDL
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Thermoplasma volcanium Probable N-glycosylase/DNA lyase(ogg)
貨號：

CSB-MP857124TDL
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

ogg
Uniprot No.：

Q97CP1
別名：

ogg; TV0060; TVG0063493; Probable N-glycosylase/DNA lyase [Includes: 8-oxoguanine DNA glycosylase; EC 3.2.2.-); DNA-(apurinic or apyrimidinic site) lyase; AP lyase; EC 4.2.99.18)]
種屬：

Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1)
蛋白長度：

full length protein
表達區(qū)域：

1-204
氨基酸序列

MDFNQYFLPL FQGEASLIIN KKVEEFKLFD RKNKDALFEE LCFCILAANT SARMALDMQN RIGKGFLYLS ENELREKLKA FKYRFYNVRP RYIVESRDIV DELPYIVSMD NKEEARDLLV ENVYGFGYKE ASHFLRNVGV FDFAILDKHI LEWLSRYFQV KKNTSRKNYL YNESIFREIA KSVGMEPGVL DLYIWYMETG TVIK
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Catalyzes the excision of an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine = 8-oxoG) from DNA. Also cleaves the DNA backbone at apurinic/apyrimidinic sites (AP sites). Prefers oligomers containing 8-oxoG:C, 8-oxoG:T and 8-oxoG:G base pairs, and is less effective on oligomers containing 8-oxoG:A mispairs.
基因功能參考文獻：
1. These results indicate that the TVG_RS00315-encoded 8-Oxoguanine DNA Glycosylase enzyme displays DNA glycosylase, and apurinic/apyrimidinic (AP) lyase activities on 7,8-dihydro-8-oxoguanine/N (where N is A, T, G, or C) mismatch, yet it cannot eliminate U from U/G or T from T/G, as mismatch glycosylases can. PMID: 27799846
蛋白家族：

Type-2 OGG1 family
數(shù)據(jù)庫鏈接：

KEGG: tvo:TVG0063493

STRING: 273116.TVN0062