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  4. Recombinant Schizosaccharomyces pombe Uncharacterized homeobox protein C21B10.13c (SPBC21B10.13c)

Recombinant Schizosaccharomyces pombe Uncharacterized homeobox protein C21B10.13c (SPBC21B10.13c)

  • 中文名稱：
    龐貝裂殖酵母yox1重組蛋白
  • 貨號：
    CSB-YP328193SXV
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母yox1重組蛋白
  • 貨號：
    CSB-EP328193SXV
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母yox1重組蛋白
  • 貨號：
    CSB-EP328193SXV-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    龐貝裂殖酵母yox1重組蛋白
  • 貨號：
    CSB-BP328193SXV
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    龐貝裂殖酵母yox1重組蛋白
  • 貨號：
    CSB-MP328193SXV
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    yox1
  • Uniprot No.：
  • 別名：
    yox1; SPBC21B10.13c; MBF complex negative regulatory component yox1
  • 種屬：
    Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-201
  • 氨基酸序列
    MSLSDSPSKS GNTGKDLISN NEAKNHEDEE THQKKRRRRT TDAEATLLEQ YFLKTPKPSL IERQELSKKL KSSMTPRELQ IWFQNKRQSL RRSNCLSRNR LEGTGENSLL RRKSTLTLCE TSTGQAELFF QSWPLHSQSV VGEMIHHEQD DYNKENKQQK VVDTTKDISR GSNGNEDSAA HQELEECARS LVELQQQCND H
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Negative regulatory component of the MBF transcription factor complex involved in cell-cycle G1/S phase-specific gene expression and more particularly DNA replication checkpoint-dependent gene expression.
  • 基因功能參考文獻：
    1. data show that Yox1 acts to co-ordinate the expression of MBF-regulated genes during the cell division cycle; data suggests that Yox1 is inactivated by the Rad3 DNA replication checkpoint via phosphorylation by the conserved Cds1 checkpoint kinase PMID: 21304269
    2. Checkpoint-dependent phosphorylation of Yox1p at Ser114, Thr115 results in de-repression of the MBF transcriptional program. PMID: 21359180
    3. phosphorylation of Yox1 when the checkpoint kinase is activated triggers the transcriptional induction of the S-phase genes PMID: 21132016
    4. Yox1 as a new regulatory MBF component in fission yeast, which is transcriptionally induced by MBF and in turn inhibits MBF-dependent transcription. PMID: 19714215
  • 亞細胞定位：
    Nucleus.
  • 數(shù)據(jù)庫鏈接：


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