Recombinant Schizosaccharomyces pombe Mediator of RNA polymerase II transcription subunit 12 (srb8), partial

中文名稱：

龐貝裂殖酵母srb8重組蛋白
貨號：

CSB-YP889216SXV
規(guī)格：
來源：

Yeast
其他：

中文名稱：

龐貝裂殖酵母srb8重組蛋白
貨號：

CSB-EP889216SXV
規(guī)格：
來源：

E.coli
其他：

中文名稱：

龐貝裂殖酵母srb8重組蛋白
貨號：

CSB-EP889216SXV-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

龐貝裂殖酵母srb8重組蛋白
貨號：

CSB-BP889216SXV
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

龐貝裂殖酵母srb8重組蛋白
貨號：

CSB-MP889216SXV
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

srb8
Uniprot No.：

Q9P6L8
別名：

srb8; med12; SPAC688.08Mediator of RNA polymerase II transcription subunit 12; Mediator complex subunit 12; Suppressor of RNA polymerase B srb8
種屬：

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

Component of the srb8-11 complex. The srb8-11 complex is a regulatory module of the Mediator complex which is itself involved in regulation of basal and activated RNA polymerase II-dependent transcription. The srb8-11 complex may be involved in the transcriptional repression of a subset of genes regulated by Mediator. It may inhibit the association of the Mediator complex with RNA polymerase II to form the holoenzyme complex.
基因功能參考文獻(xiàn)：
1. Results demonstrate that deletion of Mediator subunits Med12 and Med13 leads to a release of Cdk8 from the Mediator complex and causes advanced entry into mitosis. PMID: 25154415
亞細(xì)胞定位：

Nucleus.
蛋白家族：

Mediator complex subunit 12 family
數(shù)據(jù)庫鏈接：

KEGG: spo:SPAC688.08

STRING: 4896.SPAC688.08.1