Recombinant Schizosaccharomyces pombe Histone acetyltransferase type B catalytic subunit (hat1)

中文名稱：

龐貝裂殖酵母hat1重組蛋白
貨號(hào)：

CSB-YP890833SXV
規(guī)格：
來源：

Yeast
其他：

中文名稱：

龐貝裂殖酵母hat1重組蛋白
貨號(hào)：

CSB-EP890833SXV
規(guī)格：
來源：

E.coli
其他：

中文名稱：

龐貝裂殖酵母hat1重組蛋白
貨號(hào)：

CSB-EP890833SXV-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

龐貝裂殖酵母hat1重組蛋白
貨號(hào)：

CSB-BP890833SXV
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

龐貝裂殖酵母hat1重組蛋白
貨號(hào)：

CSB-MP890833SXV
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

hat1
Uniprot No.：

Q9UTM7
別名：

hat1; SPAC139.06; SPAC23C4.01Histone acetyltransferase type B catalytic subunit; EC 2.3.1.48
種屬：

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
蛋白長(zhǎng)度：

full length protein
表達(dá)區(qū)域：

1-378
氨基酸序列

MSAVDEWVHN ANECIEIVQV NEKHEKDCQY HPSNTYAIFG DAEVIYGYKD LNVTITYECP LMVPKLEISY SERLAPDSGV EPTDIEGTLN TYLKDRSIKV EGNSFDVHSA NSIHNYSFNG KTFKILQATV LEASEIMQHL QIFSLFFIEG GSFIDLNDPR WMVYLLYETT EDDYCLRGYC TVYKYYKWDK LIHDGIRARI SQFVILPPFQ HQGHGSQLYN AIVSTFLKNP KILDFTVEDA SEAFDSLRDH CDYKRLLSMG IFSEPDFHPS LSRQWINSKI AETKLTQRQF SRCCELAFTT KLKKLSLLER KSVRLGIKER IFRQNLDVLL QLDKSERIEK IHNAYENQFD EYKQIVKKLP KLKEDSPRKR QKLAQSSS
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Catalytic component of the histone acetylase B (HAT-B) complex. Acetylates 'Lys-12' of histone H4 which is required for telomeric silencing. Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. Involved in DNA double-strand break repair.
基因功能參考文獻(xiàn)：
1. Hat1 associates with Mis16 and acetylates lysines 5 and 12 of histone H4. Deletion of Hat1 causes loss of silencing at telomeres. PMID: 22771823
2. the role of Hat1 in DNA damage repair is evolutionarily conserved, the ability of H3 acetylation to compensate for Hat1 deletion appears to be more variable PMID: 17052979
亞細(xì)胞定位：

Cytoplasm. Nucleus.
蛋白家族：

HAT1 family
數(shù)據(jù)庫(kù)鏈接：

KEGG: spo:SPAC139.06

STRING: 4896.SPAC139.06.1