Recombinant Schizosaccharomyces pombe Histone acetyltransferase gcn5 (gcn5)

中文名稱：

龐貝裂殖酵母gcn5重組蛋白
貨號：

CSB-YP891658SXV
規(guī)格：
來源：

Yeast
其他：

中文名稱：

龐貝裂殖酵母gcn5重組蛋白
貨號：

CSB-EP891658SXV
規(guī)格：
來源：

E.coli
其他：

中文名稱：

龐貝裂殖酵母gcn5重組蛋白
貨號：

CSB-EP891658SXV-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

龐貝裂殖酵母gcn5重組蛋白
貨號：

CSB-BP891658SXV
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

龐貝裂殖酵母gcn5重組蛋白
貨號：

CSB-MP891658SXV
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

gcn5
Uniprot No.：

Q9UUK2
別名：

gcn5; SPAC1952.05Histone acetyltransferase gcn5; EC 2.3.1.48
種屬：

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
蛋白長度：

full length protein
表達(dá)區(qū)域：

1-454
氨基酸序列

MSNSLNDQTR PPDSSVVDST SSNFPNASND SVHDKPVKQD EQSNPNVREA IANSDGQESL AVKENKDTES SSSHFVPNGV SNSKKRKLVA TDLDVDFDIS SVRVTEKPSV LEEKSGVIQF RVVSNDDTAD SMIMLTGLKN IFMKQLPKMP KEYITRLIYD RNHLSMTIVK DNLHVVGGIT YRPFEQRGFA EIVFCAIASN EQVRGYGSHL MNHLKDYVRG TTTIQHFLTY ADNYAIGYFK KQGFTKEITL DKSIWVGYIK DYEGGTLMQC TMIPKIKYLE ANLILAIQKA AVVSKINRIT RSNVVYPGLD VFKDGPAHIE PSQVPGLMEV GWCKEMEELS KKPRPKPFFA VLEMLFTEMQ NHPSSWPFMQ PVSKEDVPDY YEVIEHPMDL STMEFRLRNN QYESVEEFIR DAKYIFDNCR SYNDSNTTYY KNADRLEKFF QKKLRETEYS HLAD
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

功能：

Acetylates histone H2B to form H2BK11ac and H2BK16ac, histone H3 to form H3K14ac, and with a lower preference histone H4 to form H4K8ac and H4K16ac. Acetylation of histones gives a specific tag for epigenetic transcription activation.
基因功能參考文獻(xiàn)：
1. Gcn5 mediates eviction of nucleosomes positioned downstream of promoters, allowing efficient Pol II progression along the genes. PMID: 21515633
2. The histone acetyltransferase Gcn5 is required for most histone H3 acetylation around the meiotic recombination hotspot M26. Deletion of gcn5 causes a significant delay in chromatin remodeling but only partial reduction of M26 meiotic recomb. freq. [gcn5] PMID: 14988732
亞細(xì)胞定位：

Nucleus.
蛋白家族：

Acetyltransferase family, GCN5 subfamily
數(shù)據(jù)庫鏈接：

KEGG: spo:SPAC1952.05

STRING: 4896.SPAC1952.05.1