Recombinant Schizosaccharomyces pombe E3 ubiquitin-protein ligase brl1 (brl1), partial

中文名稱：

Recombinant Schizosaccharomyces pombe E3 ubiquitin-protein ligase brl1(brl1) ,partial
貨號：

CSB-YP633212SXV
規(guī)格：
來源：

Yeast
其他：

中文名稱：

Recombinant Schizosaccharomyces pombe E3 ubiquitin-protein ligase brl1(brl1) ,partial
貨號：

CSB-EP633212SXV
規(guī)格：
來源：

E.coli
其他：

中文名稱：

Recombinant Schizosaccharomyces pombe E3 ubiquitin-protein ligase brl1(brl1) ,partial
貨號：

CSB-EP633212SXV-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Schizosaccharomyces pombe E3 ubiquitin-protein ligase brl1(brl1) ,partial
貨號：

CSB-BP633212SXV
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Schizosaccharomyces pombe E3 ubiquitin-protein ligase brl1(brl1) ,partial
貨號：

CSB-MP633212SXV
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

brl1
Uniprot No.：

Q1MTQ0
別名：

brl1; rfp2; SPCC1919.15; SPCC790.01E3 ubiquitin-protein ligase brl1; EC 2.3.2.27; BRE1-like protein 1; RING finger protein 2; RING-type E3 ubiquitin transferase brl1
種屬：

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

功能：

E3 ubiquitin-protein ligase which belongs to the histone H2B ubiquitin ligase complex (HULC) which mediates monoubiquitination of histone H2B to form H2BK123ub1. H2BK123ub1 gives a specific tag for epigenetic transcriptional activation and is also a prerequisite for H3K4me and H3K79me formation.
基因功能參考文獻(xiàn)：
1. Mst2 binds to all transcriptionally active regions genome-wide. Besides acetylating histone H3K14, Mst2 also acetylates Brl1, a component of the histone H2B ubiquitin ligase complex. Brl1 acetylation increases histone H2B ubiquitination, which positively feeds back on transcription and prevents ectopic heterochromatin assembly. PMID: 28648780
亞細(xì)胞定位：

Nucleus.
蛋白家族：

BRE1 family
數(shù)據(jù)庫鏈接：

KEGG: spo:SPCC1919.15

STRING: 4896.SPCC1919.15.1