Recombinant Schizosaccharomyces pombe DNA repair protein rad60 (rad60)

中文名稱：

龐貝裂殖酵母rad60重組蛋白
貨號：

CSB-YP891502SXV
規(guī)格：
來源：

Yeast
其他：

中文名稱：

龐貝裂殖酵母rad60重組蛋白
貨號：

CSB-EP891502SXV
規(guī)格：
來源：

E.coli
其他：

中文名稱：

龐貝裂殖酵母rad60重組蛋白
貨號：

CSB-EP891502SXV-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

龐貝裂殖酵母rad60重組蛋白
貨號：

CSB-BP891502SXV
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

龐貝裂殖酵母rad60重組蛋白
貨號：

CSB-MP891502SXV
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

rad60
Uniprot No.：

Q9USX3
別名：

rad60; SPBC1921.02; DNA repair protein rad60
種屬：

Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
蛋白長度：

full length protein
表達(dá)區(qū)域：

1-406
氨基酸序列

MDNLDEDDLA FFSKPIKKPP LNYAKQLIAS SSDSEEESEL DTNKQALEHI NAQKNITHNE NKSAEPLSRQ STILDADEGN QDVSDTTPNA CLNEGRHSPK SAISCVTQPV SPVYNTRAAA NLRNNSINSE AALSTTSSLL DDDFARRLEE IDRQVQEFEK SSSDMDVQIH THKREIEEDD DNTSADVPLL KHSKSDHSTL YHSKSEFSTN EPVISVVLQL AVIGQRIPNS NISLPRDWEA PLFFKVKSNQ QFRRVRIAYS ERKKVDNVVL VFQNQRLWDY GTPKGAGMLK VDTRLVVHAY CHSDFISLKR IKELEVEKLS SVTEDSTAQT CKLITLLLRS SKSEDLRLSI PVDFTVKDLI KRYCTEVKIS FHERIRLEFE GEWLDPNDQV QSTELEDEDQ VSVVLD
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

功能：

Required for repair of DNA double strand breaks which occur during replication, or induced by UV or gamma radiation, via recombination between sister chromatids. This has a subsequent role in the maintenance of chromosome structure. May work in conjunction with the Smc5-Smc6 complex.
基因功能參考文獻(xiàn)：
1. These results suggest that Rhp51 and Rad60 are required for the restoration of a stalled or collapsed replication fork after release from the arrest of DNA replication [Rhb51][Rad60] PMID: 16354704
2. role in protecting genome stability against spontaneous Top1-mediated DNA damage PMID: 21408210
3. SUMO-like domains 1 of Rad60 is essential for viability, while SUMO-like domains 2 is not. PMID: 20885950
4. results provide a mechanistic basis for the near-synonymous roles of Rad60 and SUMO in survival of genotoxic stress and suggest unprecedented DNA-damage-response functions for SLDs in regulating sumoylation PMID: 19363481
亞細(xì)胞定位：

Nucleus.
數(shù)據(jù)庫鏈接：

KEGG: spo:SPBC1921.02

STRING: 4896.SPBC1921.02.1