Recombinant Schizosaccharomyces pombe Cell division cycle protein 48 (cdc48), partial
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中文名稱：Recombinant Schizosaccharomyces pombe Cell division cycle protein 48(cdc48) ,partial
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貨號：CSB-YP885811SXV
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規格：
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來源：Yeast
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其他：
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中文名稱：Recombinant Schizosaccharomyces pombe Cell division cycle protein 48(cdc48) ,partial
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貨號：CSB-EP885811SXV
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規格：
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來源：E.coli
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其他：
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中文名稱：Recombinant Schizosaccharomyces pombe Cell division cycle protein 48(cdc48) ,partial
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貨號：CSB-EP885811SXV-B
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規格：
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來源：E.coli
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共軛：Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
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其他：
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中文名稱：Recombinant Schizosaccharomyces pombe Cell division cycle protein 48(cdc48) ,partial
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貨號：CSB-BP885811SXV
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規格：
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來源：Baculovirus
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其他：
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中文名稱：Recombinant Schizosaccharomyces pombe Cell division cycle protein 48(cdc48) ,partial
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貨號：CSB-MP885811SXV
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規格：
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來源：Mammalian cell
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其他：
產品詳情
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純度：>85% (SDS-PAGE)
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基因名：cdc48
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Uniprot No.：
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別名：cdc48; SPAC1565.08; SPAC6F12.01Cell division cycle protein 48; EC 3.6.4.6; Transitional endoplasmic reticulum ATPase homolog
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種屬：Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
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蛋白長度：Partial
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蛋白標簽：Tag?type?will?be?determined?during?the?manufacturing?process.
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially. -
產品提供形式：Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand. -
復溶：We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
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儲存條件：Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保質期：The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期：Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
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注意事項：Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Datasheet ：Please contact us to get it.
產品評價
靶點詳情
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功能：ATP-dependent chaperone which probably uses the energy provided by ATP hydrolysis to generate mechanical force to unfold substrate proteins, disassemble protein complexes, and disaggregate protein aggregates. By recruiting and promoting the degradation of ubiquitinated proteins, plays a role in the ubiquitin fusion degradation (UFD) pathway. Has a role in the endoplasmic reticulum-associated degradation (ERAD) pathway which mediates the cytoplasmic elimination of misfolded proteins exported from the ER. Involved in spindle disassembly. Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. CDC48 may provide the mechanical force that dislodges the polyubiquitinated nascent peptides from the exit channel. Required for ribophagy, a process which relocalizes ribosomal particles into the vacuole for degradation in response to starvation.
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基因功能參考文獻：
- Data show that cell cycle protein Cdc48-353 mutant is structurally compromized at the restrictive temperature. PMID: 25658828
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亞細胞定位：Cytoplasm. Nucleus.
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蛋白家族：AAA ATPase family
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數據庫鏈接：
KEGG: spo:SPAC1565.08
STRING: 4896.SPAC1565.08.1
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