Recombinant Saccharomyces cerevisiae Vacuolar calcium ion transporter (VCX1), partial

中文名稱：

釀酒酵母VCX1重組蛋白
貨號：

CSB-YP859096SVG
規格：
來源：

Yeast
其他：

中文名稱：

釀酒酵母VCX1重組蛋白
貨號：

CSB-EP859096SVG
規格：
來源：

E.coli
其他：

中文名稱：

釀酒酵母VCX1重組蛋白
貨號：

CSB-EP859096SVG-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

釀酒酵母VCX1重組蛋白
貨號：

CSB-BP859096SVG
規格：
來源：

Baculovirus
其他：

中文名稱：

釀酒酵母VCX1重組蛋白
貨號：

CSB-MP859096SVG
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

VCX1
Uniprot No.：

Q99385
別名：

VCX1; HUM1; MNR1; YDL128W; Vacuolar calcium ion transporter; High copy number undoes manganese protein 1; Manganese resistance 1 protein; Vacuolar Ca(2+)/H(+) exchanger
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Has a role in promoting intracellular calcium ion sequestration via the exchange of calcium ions for hydrogen ions across the vacuolar membrane. Involved also in manganese ion homeostasis via its uptake into the vacuole.
基因功能參考文獻：
1. Importantly, ESCRT gene deletions in the vcx1Delta strain did not result in an increase in the CaCl2-invoked drop in the intracellular pH levels of cells, which demonstrates a genetic interaction between VCX1 and studied ESCRT genes. PMID: 25690770
2. crystal structure of the Saccharomyces cerevisiae vacuolar Ca(2+)/H(+) exchanger (Vcx1) at 2.3 A resolution in a cytosol-facing, substrate-bound conformation PMID: 23685453
3. analysis of the relative importance of Nhx1p, Vnx1p, and Vcx1p in the vacuolar accumulation of monovalent cations PMID: 20709757
4. Vcx1 protein has an odd number of transmembrane domains; its termini are located on opposite sides of the membrane, with the N-terminus in the cytoplasm. PMID: 18447831
亞細胞定位：

Vacuole membrane; Multi-pass membrane protein.
蛋白家族：

Ca(2+):cation antiporter (CaCA) (TC 2.A.19) family
數據庫鏈接：

KEGG: sce:YDL128W

STRING: 4932.YDL128W