Recombinant Saccharomyces cerevisiae Protein OS-9 homolog (YOS9), partial

中文名稱：

釀酒酵母YOS9重組蛋白
貨號：

CSB-YP860329SVG
規格：
來源：

Yeast
其他：

中文名稱：

釀酒酵母YOS9重組蛋白
貨號：

CSB-EP860329SVG
規格：
來源：

E.coli
其他：

中文名稱：

釀酒酵母YOS9重組蛋白
貨號：

CSB-EP860329SVG-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

釀酒酵母YOS9重組蛋白
貨號：

CSB-BP860329SVG
規格：
來源：

Baculovirus
其他：

中文名稱：

釀酒酵母YOS9重組蛋白
貨號：

CSB-MP860329SVG
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

YOS9
Uniprot No.：

Q99220
別名：

YOS9; YDR057W; D4222; Protein OS-9 homolog
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Lectin involved in the quality control of the secretory pathway. As a member of the endoplasmic reticulum-associated degradation lumenal (ERAD-L) surveillance system, targets misfolded endoplasmic reticulum lumenal glycoproteins for degradation. The recognition of targets is N-glycan specific. Functions in recruiting misfolded protein substrates in conjunction with HRD3.
基因功能參考文獻：
1. Yos9p and Hrd1p mediate ER retention of misfolded proteins in the early stage of ERAD, which constitutes a process separable from the later degradation step. PMID: 22298424
2. Structural and biochemical basis of Yos9 protein dimerization and possible contribution to self-association of 3-hydroxy-3-methylglutaryl-coenzyme A reductase degradation ubiquitin-ligase complex. PMID: 22262864
3. Data show that Yos9 slows the degradation of the unglycosylated ERAD substrate CPY *0000. PMID: 21871892
4. Yos9p has a previously unrecognized role in the quality control of nonglycosylated proteins PMID: 21737688
5. Data suggest that Yos9p plays a critical role in the bipartite recognition of terminally misfolded glycoproteins. PMID: 16168370
6. Data show that Yos9p binds directly to substrates to discriminate misfolded from folded proteins. PMID: 16168371
7. Data show that Yos9 protein in Saccharomyces cerevisiae is essential for efficient degradation of mutant glycoproteins. PMID: 16168372
8. Yos9p ensures that only terminally misfolded polypeptides are degraded. PMID: 16845381
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亞細胞定位：

Endoplasmic reticulum membrane; Peripheral membrane protein; Lumenal side.
蛋白家族：

OS-9 family
數據庫鏈接：

KEGG: sce:YDR057W

STRING: 4932.YDR057W