Recombinant Saccharomyces cerevisiae Meiotic recombination protein REC8 (REC8), partial

中文名稱(chēng)：

釀酒酵母REC8重組蛋白
貨號(hào)：

CSB-YP613204SVG
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱(chēng)：

釀酒酵母REC8重組蛋白
貨號(hào)：

CSB-EP613204SVG
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱(chēng)：

釀酒酵母REC8重組蛋白
貨號(hào)：

CSB-EP613204SVG-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱(chēng)：

釀酒酵母REC8重組蛋白
貨號(hào)：

CSB-BP613204SVG
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱(chēng)：

釀酒酵母REC8重組蛋白
貨號(hào)：

CSB-MP613204SVG
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

REC8
Uniprot No.：

Q12188
別名：

REC8; SPO69; YPR007C; LPZ7C; Meiotic recombination protein REC8; Cohesin REC8; Sporulation protein 69
種屬：

Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
蛋白長(zhǎng)度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Replaces the SCC1 mitosis-specific cohesin to ensure sister chromatid cohesion during meiosis. Is cleaved by ESP1 shortly before the first meiotic division, and dissociates from chromatin, allowing sister chromatids to segregate. Is protected from cleavage by SPO13.
基因功能參考文獻(xiàn)：
1. Sister-chromatid cohesion is not necessary for activation of REC8 gene expression. PMID: 21270391
2. Condensin enhances the association of Cdc5 with chromosomes and its phosphorylation of cohesin, which in turn likely stimulates cohesin removal. PMID: 16269332
3. These findings define Rec8 as a key determinant of meiotic chromosome morphogenesis and a central player in multiple meiotic events. PMID: 19073884
4. Results suggest that Rec8 would prearrange the distribution of Spo11 along chromosomes and will provide clues to understanding temporal and spatial regulation of DSB formation. PMID: 19439448
亞細(xì)胞定位：

Nucleus. Chromosome. Chromosome, centromere.
蛋白家族：

Rad21 family
數(shù)據(jù)庫(kù)鏈接：

KEGG: sce:YPR007C

STRING: 4932.YPR007C