Recombinant Rat Drebrin-like protein (Dbnl)

中文名稱：

Recombinant Rat Drebrin-like protein(Dbnl)
貨號(hào)：

CSB-YP862356RA
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

Recombinant Rat Drebrin-like protein(Dbnl)
貨號(hào)：

CSB-EP862356RA
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：

Recombinant Rat Drebrin-like protein(Dbnl)
貨號(hào)：

CSB-EP862356RA-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Rat Drebrin-like protein(Dbnl)
貨號(hào)：

CSB-BP862356RA
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

Recombinant Rat Drebrin-like protein(Dbnl)
貨號(hào)：

CSB-MP862356RA
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Dbnl
Uniprot No.：

Q9JHL4
別名：

Dbnl; Sh3p7Drebrin-like protein; Actin-binding protein 1; Abp1; SH3 domain-containing protein 7
種屬：

Rattus norvegicus (Rat)
蛋白長(zhǎng)度：

full length protein
表達(dá)區(qū)域：

1-436
氨基酸序列

MAVNLSRNGP ALQEAYVRVV TEKSPTDWAL FTYEGNSNDI RVAGTGEGGL EELVEELNSG KVMYAFCRVK DPNSGLPKFV LINWTGEGVN DVRKGACANH VSTMANFLKG AHVTINARAE EDVEPECIME KVAKASGANY SFHKESSCFQ DVGPQAPVGS VYQKTNAVSE IKRVGKDNFW AKAEKEEENR RLEEKRRAEE EKQRLEEERR ERELQEAARR EQRYQEQHRS AGPPSPSSRT GELEQEVVSR SRQEWESAGQ QAPHPREIFK QKERAMSTTS VSSSQPGKLR SPFLQKQFTQ PEASYGREPT SPVSRPAAGV CEELAPSTPP SAQTDDEPTY EVPSEQETLY EEPPPVQQPG AGSGHIDNYM QSQDLSGQGL CARALYDYQA ADDTEISFDP ENLITGIEVI DEGWWRGYGP DGHFGMFPAN YVELIE
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Adapter protein that binds F-actin and DNM1, and thereby plays a role in receptor-mediated endocytosis. Required for the formation of organized podosome rosettes. May act as a common effector of antigen receptor-signaling pathways in leukocytes. Acts as a key component of the immunological synapse that regulates T-cell activation by bridging TCRs and the actin cytoskeleton to gene activation and endocytic processes. Plays a role in the reorganization of the actin cytoskeleton, formation of cell projections, such as neurites, in neuron morphogenesis and synapse formation via its interaction with WASL and COBL. Does not bind G-actin and promote actin polymerization by itself.
基因功能參考文獻(xiàn)：
1. Findings reveal a novel signaling adaptor protein, HIP-55, which negatively regulates the beta-AR-mediated ERK proliferative pathway and Cardia Fibroblast proliferation. PMID: 24802081
亞細(xì)胞定位：

Cytoplasm, cytoskeleton. Cell projection, lamellipodium. Cell projection, ruffle. Cytoplasm, cell cortex. Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction, synapse. Perikaryon. Cell projection, neuron projection. Cell projection, dendrite. Cell junction, synapse, postsynaptic density. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, clathrin-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, podosome. Early endosome.
蛋白家族：

ABP1 family
組織特異性：

Detected in brain (at protein level). Widely expressed in brain with highest levels in hippocampus and cerebral cortex. Located primarily in dendrites and, in moderate amounts, in cell bodies. Isoform 1 and isoform 3 are the predominant isoforms in brain.
數(shù)據(jù)庫(kù)鏈接：

KEGG: rno:83527

STRING: 10116.ENSRNOP00000017375

UniGene: Rn.4115