Recombinant Rat Centromere/kinetochore protein zw10 homolog (Zw10)

中文名稱：

大鼠Zw10重組蛋白
貨號：

CSB-YP703288RA
規格：
來源：

Yeast
其他：

中文名稱：

大鼠Zw10重組蛋白
貨號：

CSB-EP703288RA
規格：
來源：

E.coli
其他：

中文名稱：

大鼠Zw10重組蛋白
貨號：

CSB-EP703288RA-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

大鼠Zw10重組蛋白
貨號：

CSB-BP703288RA
規格：
來源：

Baculovirus
其他：

中文名稱：

大鼠Zw10重組蛋白
貨號：

CSB-MP703288RA
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Zw10
Uniprot No.：

Q4V8C2
別名：

Zw10; Centromere/kinetochore protein zw10 homolog
種屬：

Rattus norvegicus (Rat)
蛋白長度：

Full Length of Mature Protein
表達區域：

2-777
氨基酸序列

ASFVTEVLA HSGSLEKEDL GTRISRLTRR VEEIKGEVCN MISKKYSEFL PTMQSAQALV TQVDTLSNDI DQLKSRIETE VCRDLHISTV EFTNLKQRLE RDSVVLNLLK QLQEFSSAIE EYNSALAEKK YIPAARLLEE AQECLKLLKS KKCFDLKMLK SLSMELTVQK QNILYHLGED WQKLVVWKFP PSKDTSSLES CLQTELHLCT EQPEKEMTPL PSISSVLLAF SILGELPTKL KSFGQMLLKY ILKPLVTCPS LHAVIERQPN SVSICFQSLA TDSEHPPPPE AFAKIQLVLE VLQKQLLDLP LDADLEIGKV PEIVLAEMLG EVIWEDLSDC LIRNCLVYSI PTNSSKLQQY EEIIQSTEEF EKSLKEMRFL KGDTTDLLKY ARNINSHFAN KKCQDVIVAA RHLMTSEIHN TVKIGPDCEE TLPDLPSPDA DHRLQVQVCK VQFTDAGNLE PETSLDPRSF SLPTCRISEA VKKLMELAYQ TLLEATTSSD QCAVQLFYSV RNIFHLFHDV VPTYHKENLQ KLPQLAAIHH NNCMYIAHHL LTLGHQFRSR LTPILCDGTT TFVDLVPGFR RLGTECFLAQ MRTQKGELLE RLSSARSFAN MDDEENYSAA SKAVRQVLHQ LKRLGIVWQD VLPVNIYCKA MGTLLNTVIA EMIGRITALE DISTEDGDRL YSLCKTVMDE GPQVFAPLSD ENKNKKYQEE VPVYVSKWMP FKELMIMLQA SLQEIGDRWA DGKGPLATAF PSSEVKALIR ALFQNTERRA AALAKIK
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex. Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum (ER); the function is proposed to depend on its association in the interphase NRZ complex which is believed to play a role in SNARE assembly at the ER.
基因功能參考文獻：
1. targeting of ZW10 to the perinuclear Golgi region was found to depend on the perinuclear accumulation of dynactin PMID: 17560939
亞細胞定位：

Cytoplasm. Endoplasmic reticulum membrane; Peripheral membrane protein. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Lipid droplet.
蛋白家族：

ZW10 family
數據庫鏈接：

KEGG: rno:363059

STRING: 10116.ENSRNOP00000010595

UniGene: Rn.25242