Recombinant Probable tyrosyl-DNA phosphodiesterase (F52C12.1)

中文名稱：

秀麗隱桿線蟲F52C12.1重組蛋白
貨號：

CSB-YP874705CXY
規格：
來源：

Yeast
其他：

中文名稱：

秀麗隱桿線蟲F52C12.1重組蛋白
貨號：

CSB-EP874705CXY
規格：
來源：

E.coli
其他：

中文名稱：

秀麗隱桿線蟲F52C12.1重組蛋白
貨號：

CSB-EP874705CXY-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

秀麗隱桿線蟲F52C12.1重組蛋白
貨號：

CSB-BP874705CXY
規格：
來源：

Baculovirus
其他：

中文名稱：

秀麗隱桿線蟲F52C12.1重組蛋白
貨號：

CSB-MP874705CXY
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

F52C12.1
Uniprot No.：

Q9TXV7
別名：

F52C12.1; Probable tyrosyl-DNA phosphodiesterase; Tyr-DNA phosphodiesterase; EC 3.1.4.-
種屬：

Caenorhabditis elegans
蛋白長度：

full length protein
表達區域：

1-451
氨基酸序列

MKRTIQETPG PSSTTVPPPK KLNSQRNGSN LEPGSIYFTP IGGISVPRQE SESSRSLDEI LADIRPINSL HFSFMLDFEF LIGSYPPSLR EYPITLVVGA PDAPDLLKCT KNQKLVTVVG ASLPIPFGTH HTKMSILEDE DGRFHVIVST ANLVPDDWEF KTQQFYYNFG VKIASGTVPR SDFQDDLLEY LSMYRNQLDT WKQLLQKVDF SQISDRLIFS TPGYHTDPPT QRPGHPRLFR ILSEKFPFDA SYEHTERCTF VAQCSSIGSL GSAPINWFRG QFLQSLEGAN PSPKQKPAKM YLVFPSVEDV RTSCQGYAGG CSVPYRNSVH ARQKWLQGNM CKWRSNAKRR TNAVPHCKTY VKYDKKVAIW QLLTSANLSK AAWGEVSFNK SKNVEQLMIR SWEMGVLITD PSRFNIPFDY PLVPYSATDE PFVTDKKHEK PDILGCIWTP P
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. May have low 3'exonuclease activity and may be able to remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups. Has no exonuclease activity towards DNA or RNA with a 3'phosphate.
亞細胞定位：

Nucleus.
蛋白家族：

Tyrosyl-DNA phosphodiesterase family
數據庫鏈接：

KEGG: cel:CELE_F52C12.1

STRING: 6239.F52C12.1.1

UniGene: Cel.12879