Recombinant Mouse Zinc finger and SCAN domain-containing protein 10 (Zscan10)

中文名稱：

小鼠Zscan10重組蛋白
貨號(hào)：

CSB-YP661055MO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Zscan10重組蛋白
貨號(hào)：

CSB-EP661055MO
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Zscan10重組蛋白
貨號(hào)：

CSB-EP661055MO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Zscan10重組蛋白
貨號(hào)：

CSB-BP661055MO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Zscan10重組蛋白
貨號(hào)：

CSB-MP661055MO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Zscan10
Uniprot No.：

Q3URR7
別名：

Zscan10; Zfp206; Zinc finger and SCAN domain-containing protein 10; Zinc finger protein 206
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達(dá)區(qū)域：

1-782
氨基酸序列

MLAEPVPDAL EQEHPGAVKL EEDEVGEEDP RLAESRPRPE VAHQLFRCFQ YQEDMGPRAS LGRLRELCNH WLRPALHTKK QILELLVLEQ FLSVLPPHVL SRLHGQPLRD GEEVVQLLEG VPRDISHMGP LDFSFSAGKN APADIISEEQ NSPSQVPSHS PQTELPSEEI PALHPLNELP PPQPAPIRPA EPEEWRLAPS SNWPMSPEPQ EILQDPRESN PSQGPSWLEE NSRDQELAAV LESLTFEDTS EKRAWPANPL GFGSRMPDNE ELKVEEPKVT TWPVVIGAES QTEKPEVAGE PLTQTVGQET SSTGWGGTPA DGSEVVKVRG ASDAPEPQGE MQFICTYCGV NFPEMSHLQA HQLQSHPNLQ PHPSSRSFRC LWCGKTFGRS SILKLHMRTH TDERPHACHL CNRRFRQSSH LTKHLLTHSS EPAFRCAECN QGFQRRSSLM QHLLAHAQGK NLTPNPEGKT KVPEMAAVLC SHCGQTFKRR SSLKRHLRNH AKDKDHLSSE DPGSLSSSQE SNPYVCSDCG KAFRQSEQLM IHTRRVHTRE RPFSCQVCGR CFTQNSQLIS HQQIHTGEKP HACPQCSKRF VRRAGLARHL LTHGSLRPYH CAQCGKSFRQ MRDLTRHVRC HTGEKPCRCN ECGEGFTQNA HLARHQRIHT GEKPHACDIC GHRFRNSSNL ARHRRSHTGE RPYSCPTCGR SFRRNAHLQR HLITHTGSKQ EKEVPQECPE CGKSFNRSCN LLRHLLVHTG ARPYSCALCG RSFSRNSHLL RHLRTHARES LY
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價(jià)

靶點(diǎn)詳情

功能：

Embryonic stem (ES) cell-specific transcription factor required to maintain ES cell pluripotency. Can both activate and /or repress expression of target genes, depending on the context. Specifically binds the 5'-[GA]CGCNNGCG[CT]-3' DNA consensus sequence. Regulates expression of POU5F1/OCT4, ZSCAN4 and ALYREF/THOC4.
基因功能參考文獻(xiàn)：
1. The pluripotency factor ZSCAN10 is poorly expressed in A-iPSCs and addition of ZSCAN10 to the four Yamanaka factors (OCT4, SOX2, KLF4 and c-MYC) during A-iPSC reprogramming normalizes ROS-glutathione homeostasis and the DNA damage response, and recovers genomic stability. PMID: 28846095
2. Our results clearly indicate that Zscan10 is dispensable for the ability of self-renewal and differentiation in ES cells. PMID: 26592664
3. a role for Zscan10 in either maintaining progenitor cell subpopulation or impacting on fate choice decisions thereof PMID: 25111779
4. Optimized crystals diffracted to 1.85 A resolution and belonged to space group I422, with unit-cell parameters a = 67.57, c = 87.54 A. A Matthews analysis indicated the presence of one Zfp206SCAN molecule per asymmetric unit PMID: 22505416
5. Zfp206 is a regulator of embryonic stem cell differentiation that controls a set of genes expressed very early in development, most of which themselves appear to be regulators. PMID: 16971461
6. Zfp206 is an embryonic transcription factor that plays a role in regulating pluripotency of embryonic stem cells. PMID: 17628018
7. Zfp206 is a key component of the transcriptional regulatory network and together with Oct4 and Sox2 regulates differentiation of embryonic stem cells. PMID: 19740739
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亞細(xì)胞定位：

Nucleus.
組織特異性：

Embryonic stem (ES) cell-specific. Not expressed in adult, except in testis.
數(shù)據(jù)庫鏈接：

KEGG: mmu:332221

STRING: 10090.ENSMUSP00000093255

UniGene: Mm.270315