Recombinant Mouse X-linked retinitis pigmentosa GTPase regulator-interacting protein 1 (Rpgrip1), partial

中文名稱：

小鼠Rpgrip1重組蛋白
貨號：

CSB-YP887645MO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Rpgrip1重組蛋白
貨號：

CSB-EP887645MO
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Rpgrip1重組蛋白
貨號：

CSB-EP887645MO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Rpgrip1重組蛋白
貨號：

CSB-BP887645MO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Rpgrip1重組蛋白
貨號：

CSB-MP887645MO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評價
靶點詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Rpgrip1
Uniprot No.：

Q9EPQ2
別名：

Rpgrip1; X-linked retinitis pigmentosa GTPase regulator-interacting protein 1; RPGR-interacting protein 1
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評價

靶點詳情

功能：

May function as scaffolding protein. Required for normal location of RPGR at the connecting cilium of photoreceptor cells. Required for normal disk morphogenesis and disk organization in the outer segment of photoreceptor cells and for survival of photoreceptor cells.
基因功能參考文獻：
1. the results of this study indicate that the effects of FTO-associated SNPs on energy homeostasis are due in part to the effects of these genetic variations on hypothalamic FTO, RPGRIP1L, and possibly other genes. PMID: 27064284
2. RPGRIP1 has an essential role in the photoreceptor connecting cilia, and photoreceptors lacking RPGRIP1 are unable to maintain the light sensing outer segments. [review] PMID: 25414380
3. RPGRIP1 loss in photoreceptors shifts the subcellular partitioning of SDCCAG8 and NPHP4 to the membrane fraction associated to the endoplasmic reticulum. PMID: 22825473
4. RPGRIP1 is essential for rod photoreceptor outer segment morphogenesis. PMID: 19679561
5. RPGRIP1 and nephrocystin-4 interact strongly in vitro and in vivo, and that they colocalize in the retina PMID: 16339905
顯示更多

收起更多
亞細胞定位：

Cell projection, cilium.
蛋白家族：

RPGRIP1 family
組織特異性：

Expressed in the retina (at protein level).
數(shù)據(jù)庫鏈接：

KEGG: mmu:77945

STRING: 10090.ENSMUSP00000107230

UniGene: Mm.21662