Recombinant Mouse WASP homolog-associated protein with actin, membranes and microtubules (Whamm)

中文名稱：

小鼠Whamm重組蛋白
貨號：

CSB-YP701142MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Whamm重組蛋白
貨號：

CSB-EP701142MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Whamm重組蛋白
貨號：

CSB-EP701142MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Whamm重組蛋白
貨號：

CSB-BP701142MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Whamm重組蛋白
貨號：

CSB-MP701142MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Whamm
Uniprot No.：

Q571B6
別名：

Whamm; Kiaa1971; Whdc1WASP homolog-associated protein with actin; membranes and microtubules; WAS protein homology region 2 domain-containing protein 1; WH2 domain-containing protein 1
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-793
氨基酸序列

MDSEQPDSLD GWVPLREDLF PEPERHQLRF LVAWNAAKGQ FAVTCHDRTA QRRRRERREA GDGGCSWAGV LSPAGFRGAH RQLAALWPAL EPCFPPLPPE LDAASGAGWG LGRGLWALLW PLLWPAPADP GDSALQELCR QLEHYLGLAA EGCGGATVRD VLFPAPGDSA DCEGLSEFRE RTLRARLGQT ATRLHQVLQD HGKANTMVAL MKVYQEEDEL YQELVTMATT FFQYLLQPFR DMREVATSCK LGILKSLDED ELGPRRVAAL QKEASEWTRQ AEEAVGSIQD ITVNYFKETV TALTGMQKQM EQDQKRFGQA AWATAMPRLE NLKLMLARET LQLMRAKELC LKHRQAEIQR KVEDLPRQGK QLDVVDELEI QCYEIQLELY DVKLEMLRNE ETILVTRLDS VKRLITEKQA EVIYYDPCES PEELQSLAPD LELHLGDNRE LRALSQQCQR LEAQRGRICS RRALLRNRKD HCRENHQLRL QQAKQSLRHL HQHHSIQMKR DKVKEEEQKK KEWIDHERQK TLERLRAYKE KCPAHRSALK TTCSESMVSN LPGGRSQKRL STAHHHKTAH PASSKTGSAV PLPEASVRPP EHQDPCGSVP VQAFVPVSDQ TLSGSSEDLS LPPQPPAPPL PPPPPPPPPP PLPPALSSFQ GTTHQNLGLR TLATEDRPLP LACDPSAGRP CDYQGPGSMD EVLASLRQGK ASLRKVETPT LPHPGTSVNE QVLAAIRQGV QLKKVHTGQG VDPGKKSTSD LERSIREALE RIKKVSADSE EDNDEPSPTE WDR
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Acts as a nucleation-promoting factor (NPF) that stimulates Arp2/3-mediated actin polymerization both at the Golgi apparatus and along tubular membranes. Involved as a regulator of Golgi positioning and morphology. Its activity in membrane tubulation requires F-actin and interaction with microtubules. Proposed to use coordinated actin-nucleating and microtubule-binding activities of distinct WHAMM molecules to drive membrane tubule elongation; when MT-bound can recruit and remodel membrane vesicles but is prevented to activate the Arp2/3 complex. Required for RhoD-dependent actin reorganization such as in cell adhesion and cell migration. Participates in vesicle transport between the reticulum endoplasmic and the Golgi complex.
基因功能參考文獻：
1. data suggest that WHAMM is required for peripheral spindle migration and asymmetric cytokinesis during mouse oocyte maturation PMID: 23160625
亞細胞定位：

Cytoplasm. Endoplasmic reticulum-Golgi intermediate compartment. Cytoplasmic vesicle membrane. Golgi apparatus, cis-Golgi network.
數據庫鏈接：

KEGG: mmu:434204

STRING: 10090.ENSMUSP00000128881

UniGene: Mm.181641