Recombinant Mouse Tyrosine-protein kinase SgK223 (Sgk223), partial

中文名稱：

小鼠PRAG1重組蛋白
貨號：

CSB-YP684981MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠PRAG1重組蛋白
貨號：

CSB-EP684981MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠PRAG1重組蛋白
貨號：

CSB-EP684981MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠PRAG1重組蛋白
貨號：

CSB-BP684981MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠PRAG1重組蛋白
貨號：

CSB-MP684981MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

PRAG1
Uniprot No.：

Q571I4
別名：

Prag1; D8Ertd82e; Nack; Sgk223Inactive tyrosine-protein kinase PRAG1; Notch activation complex kinase; PEAK1-related kinase-activating pseudokinase 1; Sugen kinase 223; Tyrosine-protein kinase SgK223
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Catalytically inactive protein kinase that acts as a scaffold protein. Functions as an effector of the small GTPase RND2, which stimulates RhoA activity and inhibits NGF-induced neurite outgrowth. Promotes Src family kinase (SFK) signaling by regulating the subcellular localization of CSK, a negative regulator of these kinases, leading to the regulation of cell morphology and motility by a CSK-dependent mechanism. Acts as a critical coactivator of Notch signaling.
基因功能參考文獻：
1. Also known as SgK223, a member of the NKF3 family of protein kinases predicted to be catalytically inactive. PMID: 15289607
亞細胞定位：

Cytoplasm. Nucleus. Cell junction, focal adhesion. Note=Colocalized with NOTCH1 in the nucleus (PubMed:25038227).
蛋白家族：

Protein kinase superfamily
數據庫鏈接：

KEGG: mmu:244418

STRING: 10090.ENSMUSP00000106118

UniGene: Mm.244971