Recombinant Mouse Tubulin--tyrosine ligase-like protein 12 (Ttll12)

中文名稱：

小鼠Ttll12重組蛋白
貨號：

CSB-YP659719MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Ttll12重組蛋白
貨號：

CSB-EP659719MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Ttll12重組蛋白
貨號：

CSB-EP659719MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Ttll12重組蛋白
貨號：

CSB-BP659719MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Ttll12重組蛋白
貨號：

CSB-MP659719MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Ttll12
Uniprot No.：

Q3UDE2
別名：

Ttll12; Tubulin--tyrosine ligase-like protein 12; Inactive tubulin--tyrosine ligase-like protein 12
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-639
氨基酸序列

MEIQSGPQPG SPGRAERLNA RLLDEFVSLH GPTLRASGVP ERLWGRLLHK LEHEVFDAGE MFGIMQVEEV EEAEDEAARE AQRKQPNPGG ELCYKVIVTS ESGVRADDPN SIFLIDHAWT CRVEHARKQL QQVPGLLHRM ANLMGIEFHG EVPSPEVVAL VLEEMWKFNQ TYQLAHGTAE EKVPVWYIMD EFGSRIQHSD MPSFATAPFF YMPQQVAYTL LWPLRDLDTG EEVTRDFAYG EADPLIRKCM LLPWAPADML DLSFSTPEPP AKYYQAILEE NKEKLPLAIS PVARPQGHVF RVHCDVQQVL GHLTHPRFTF TDSEADADIF FHFSHFKDYM KLSQESPQVL LNQFPCENLL TVKDCLASIA RRAGGPEGPP WLPRTFNLRT ELPQFVSYFQ HRERRGEDNH WICKPWNLAR SLDTHVTNNL HSIIRHREST PKVVSKYIES PVLFLREDVG NVKFDIRYIV LLRSVRPLRL FAYDVFWLRF SNRPFALDDL DDYEKHFTVM NYDPDVVLKQ VHYNEFIPQF EKQYPEFPWS DVQAEIFKAF TELFQVACAK PPPMGLCDYP SSRAMYAIDL MLNWDNHPDG KRVMQPQILE VNFNPDCERA CRYHPSFFND VFSTLFLDET DNCHVTRII
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Negatively regulates post-translational modifications of tubulin, including detyrosination of the C-terminus and polyglutamylation of glutamate residues. Also, indirectly promotes histone H4 trimethylation at 'Lys-20' (H4K20me3). Probably by controlling tubulin and/or histone H4 post-translational modifications, plays a role in mitosis and in maintaining chromosome number stability. During RNA virus-mediated infection, acts as a negative regulator of the DDX58/RIG-I pathway by preventing MAVS binding to TBK1 and IKBKE.
亞細胞定位：

Cytoplasm. Midbody. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Nucleus.
組織特異性：

Widely expressed with highest levels in brain, kidney, liver, lung, muscle and testis.
數據庫鏈接：

KEGG: mmu:223723

STRING: 10090.ENSMUSP00000016901

UniGene: Mm.46778