Recombinant Mouse Tripartite motif-containing protein 40 (Trim40)

中文名稱：

小鼠Trim40重組蛋白
貨號：

CSB-YP668897MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Trim40重組蛋白
貨號：

CSB-EP668897MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Trim40重組蛋白
貨號：

CSB-EP668897MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Trim40重組蛋白
貨號：

CSB-BP668897MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Trim40重組蛋白
貨號：

CSB-MP668897MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Trim40
Uniprot No.：

Q3UWA4
別名：

Trim40; Gm319; Tripartite motif-containing protein 40; Probable E3 NEDD8-protein ligase
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達區域：

1-246
氨基酸序列

MGSLDKDNQD ICPICLDPLK EAVSTDCRHL FCRMCLTQHM DKASVSGILS CPVCRKPCSE GVLGDNYICH THQKRVRRFC EASGHLLCEE CLQSPEHQSH TELSIENAIS HYKERLNRRS RKLRKDLGNL QQLKAQEKKM LQALQVDCEC HRLRTDLQNQ DQTKEQLKAL PWHWLDQEDL PEEVAKIFSF SEAVTQLSIL VSGLERMAKD LDASTLKDAS DLLDRSAPQK LEGLLSRVSP AGPKLS
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

E3 ubiquitin-protein ligase that plays a role in the limitation of the innate immune response. Mediates inhibition of the RLR signaling pathway by ubiquitinating DDX58 and IFIH1 receptors, leading to their proteasomal degradation. Promotes also the neddylation of IKBKG/NEMO, stabilizing NFKBIA, and thereby inhibiting of NF-kappa-B nuclear translocation and activation.
基因功能參考文獻：
1. TRIM40 binds to MDA5 and RIG-I and promotes their K27- and K48-linked polyubiquitination via its E3 ligase activity, leading to their proteasomal degradation. TRIM40 deficiency enhances RLR-triggered signaling. PMID: 29117565
蛋白家族：

TRIM/RBCC family
數據庫鏈接：

KEGG: mmu:195359

STRING: 10090.ENSMUSP00000084400

UniGene: Mm.32606