Recombinant Mouse Transcription factor Sp5 (Sp5)

中文名稱：

小鼠Sp5重組蛋白
貨號(hào)：

CSB-YP881297MO
規(guī)格：
來源：

Yeast
其他：

中文名稱：

小鼠Sp5重組蛋白
貨號(hào)：

CSB-EP881297MO
規(guī)格：
來源：

E.coli
其他：

中文名稱：

小鼠Sp5重組蛋白
貨號(hào)：

CSB-EP881297MO-B
規(guī)格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Sp5重組蛋白
貨號(hào)：

CSB-BP881297MO
規(guī)格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Sp5重組蛋白
貨號(hào)：

CSB-MP881297MO
規(guī)格：
來源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Sp5
Uniprot No.：

Q9JHX2
別名：

Sp5; Transcription factor Sp5
種屬：

Mus musculus (Mouse)
蛋白長度：

full length protein
表達(dá)區(qū)域：

1-398
氨基酸序列

MAAVAVLRND SLQAFLQDRT PSASPDLGKH SPLALLAATC SRIGQPGAAA APDFLQVPYD PALGSPSRLF HPWTADMPAH SPGALPPPHP SLGLTPQKTH LQPSFGAAHE LPLTPPADPS YPYEFSPVKM LPSSMAALPA SCAPAYVPYA AQAALPPGYS NLLPPPPPPP PPPTCRQLSP APAPDDLPWW SIPQSGAGPG SSGVPGTSLS SACAGPPHAP RFPASAAAAA AAAAALQRGL VLGPSDFAQY QSQIAALLQT KAPLAATARR CRRCRCPNCQ AAGGAPEAEP GKKKQHVCHV PGCGKVYGKT SHLKAHLRWH TGERPFVCNW LFCGKSFTRS DELQRHLRTH TGEKRFACPE CGKRFMRSDH LAKHVKTHQN KKLKVAEAGV KRENPRDL
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Binds to GC boxes promoters elements. Probable transcriptional activator that has a role in the coordination of changes in transcription required to generate pattern in the developing embryo.
基因功能參考文獻(xiàn)：
1. Functional studies revealed that knockdown of Nanog eliminated the mESC self-renewal-promoting ability of Sp5. Finally, we demonstrated that the self-renewal-promoting function of Sp5 was largely dependent on its zinc finger domains PMID: 28961274
2. Sp5 is able to convert mouse epiblast stem cells into a naive pluripotent state. PMID: 26598557
亞細(xì)胞定位：

Nucleus.
蛋白家族：

Sp1 C2H2-type zinc-finger protein family
數(shù)據(jù)庫鏈接：

KEGG: mmu:64406

STRING: 10090.ENSMUSP00000097620

UniGene: Mm.423397