Recombinant Mouse TRAF-type zinc finger domain-containing protein 1 (Trafd1)

中文名稱：

小鼠Trafd1重組蛋白
貨號(hào)：

CSB-YP667564MO
規(guī)格：
來(lái)源：

Yeast
其他：

中文名稱：

小鼠Trafd1重組蛋白
貨號(hào)：

CSB-EP667564MO
規(guī)格：
來(lái)源：

E.coli
其他：

中文名稱：

小鼠Trafd1重組蛋白
貨號(hào)：

CSB-EP667564MO-B
規(guī)格：
來(lái)源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Trafd1重組蛋白
貨號(hào)：

CSB-BP667564MO
規(guī)格：
來(lái)源：

Baculovirus
其他：

中文名稱：

小鼠Trafd1重組蛋白
貨號(hào)：

CSB-MP667564MO
規(guī)格：
來(lái)源：

Mammalian cell
其他：

產(chǎn)品詳情
產(chǎn)品評(píng)價(jià)
靶點(diǎn)詳情

產(chǎn)品詳情

純度：

>85% (SDS-PAGE)
基因名：

Trafd1
Uniprot No.：

Q3UDK1
別名：

Trafd1; Fln29; TRAF-type zinc finger domain-containing protein 1; Protein FLN29
種屬：

Mus musculus (Mouse)
蛋白長(zhǎng)度：

Full Length of Mature Protein
表達(dá)區(qū)域：

2-580
氨基酸序列

AEFRDDQAS RLCDNCKKEI PVFNFTIHEI HCQRNIGVCP VCKEPFPKSD MDIHMAAEHC QVTCKCNKKL EKRQLKQHAE TECPLRLAVC QHCDLELSVV KLKEHEDYCG ARTELCGSCG RNVLVKELKT HPEVCGRVEE EKRTEAAIPP EAYDEPWSQD RIWIASQLLR QIEALDPPMR LPGRPLQAFE ADPFYSRTTS QRSMAAQFPV QNNLFEEQER QERNRSRQSP KDSAENNAHL DFMLALSLQN EGQATSMVEQ GFWESVPEAD PARAGPTSLG DIKGAADEIL LPCEFCEELY PEELLIDHQT SCNPSHALRS LNTGSSSIRG VEDPGTIFQN FLQQATSNQF DTLMGLSSSA AVEDSIIIPC EFCGVQLEEE VLFYHQDQCD QRPATANHRA VEGIPAQDSQ PENTSAELSR RRVKHQGDLS SGYMDDVKPE SVKGPTYSMS PNRTMNNVAS CNRLLNLPSG PRSDCQRSPP GVLKLNNSDS QDIRGQMRGS QNGPIASGHA PVIHSIQNLY PENFAPSFPH GSPGRYGAGG RSEGGRSSRV SPAAAGYHSR AAKAKPPKQQ GAGDAEEEEE
蛋白標(biāo)簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產(chǎn)品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復(fù)溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲(chǔ)存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質(zhì)期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項(xiàng)：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

功能：

Negative feedback regulator that controls excessive innate immune responses. Regulates both Toll-like receptor 4 (TLR4) and DDX58/RIG1-like helicases (RLH) pathways. May inhibit the LTR pathway by direct interaction with TRAF6 and attenuation of NF-kappa-B activation. May negatively regulate the RLH pathway downstream from MAVS and upstream of NF-kappa-B and IRF3.
基因功能參考文獻(xiàn)：
1. TRAFD1, in association with Plekhm1/Rab7-positive late endosomes-early lysosomes, has a previously unknown role in vesicle trafficking, acidification, and resorption in osteoclasts PMID: 25992615
2. FLN29 is a new negative feedback regulator of TLR signaling PMID: 16221674
組織特異性：

Expressed in skeletal muscle, brain, liver, kidney, spleen and bone marrow. Expression depends on STAT1.
數(shù)據(jù)庫(kù)鏈接：

KEGG: mmu:231712

STRING: 10090.ENSMUSP00000047475

UniGene: Mm.20488