Recombinant Mouse Sodium-coupled monocarboxylate transporter 2 (Slc5a12), partial

中文名稱：

小鼠Slc5a12重組蛋白
貨號：

CSB-YP674348MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Slc5a12重組蛋白
貨號：

CSB-EP674348MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Slc5a12重組蛋白
貨號：

CSB-EP674348MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Slc5a12重組蛋白
貨號：

CSB-BP674348MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Slc5a12重組蛋白
貨號：

CSB-MP674348MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Slc5a12
Uniprot No.：

Q49B93
別名：

Slc5a12; Smct2; Sodium-coupled monocarboxylate transporter 2; Electroneutral sodium monocarboxylate cotransporter; Low-affinity sodium-lactate cotransporter; Solute carrier family 5 member 12
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Acts as an electroneutral and low-affinity sodium (Na(+))-dependent sodium-coupled solute transporter. Catalyzes the transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, nicotinate, propionate, butyrate and beta-D-hydroxybutyrate. May be responsible for the first step of reabsorption of monocarboxylates from the lumen of the proximal tubule of the kidney and the small intestine. May play also a role in monocarboxylates transport in the retina. Mediates electroneutral uptake of lactate, with a stoichiometry of 2 Na(+) for each lactate.
基因功能參考文獻：
1. A low affinity type of SMCT2-like transporter is in operation with high capacity throughout the small intestine, playing the role as the major intestinal nicotinate uptake transporter. PMID: 22123132
2. SMCT2 was localized in the brush border of enterocytes in the intestinal villi, and SMCT2 was localized in the brush border of is a jejunal type of SCMT. PMID: 20834181
3. The cloning and characterization of slc5a12 (SMCT2) is reported. PMID: 16104846
亞細胞定位：

Apical cell membrane; Multi-pass membrane protein. Note=Detected at the brush border membrane of the kidney. Colocalizes with vimentin in Mueller cells.
蛋白家族：

Sodium:solute symporter (SSF) (TC 2.A.21) family
組織特異性：

Expressed in the cortical region of the kidney corresponding to the proximal tubule. Expressed in Mueller cells of the inner retina (at protein level). Isoform 1 is expressed in the retina, kidney, small intestine and skeletal muscle. Isoform 2 is not det
數據庫鏈接：

KEGG: mmu:241612

STRING: 10090.ENSMUSP00000047340

UniGene: Mm.277148