Recombinant Mouse Slit homolog 3 protein (Slit3), partial

中文名稱：

小鼠Slit3重組蛋白
貨號：

CSB-YP893002MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Slit3重組蛋白
貨號：

CSB-EP893002MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Slit3重組蛋白
貨號：

CSB-EP893002MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Slit3重組蛋白
貨號：

CSB-BP893002MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Slit3重組蛋白
貨號：

CSB-MP893002MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Slit3
Uniprot No.：

Q9WVB4
別名：

Slit3; Slit homolog 3 protein; Slit-3; Slit3
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May act as molecular guidance cue in cellular migration, and function may be mediated by interaction with roundabout homolog receptors.
基因功能參考文獻：
1. A small truncated recombinant SLIT3 protein increased bone mass in an osteopenic mouse model. PMID: 29764562
2. Heparan sulfate-deficient mouse endothelial cells was used to determine the co-reception function of heparan sulfate in Slit3-induced endothelial cell migration. PMID: 25325980
3. FREM1-deficient mice faithfully recapitulate many of the phenotypes seen in individuals with FREM1 deficiency and that variations in GATA4 and SLIT3 expression modulate some FREM1-related phenotypes in mice. PMID: 23536828
4. Report role of Slit3 in development of the caval veins and pericardium. PMID: 23255421
5. Robo-2-mediated targeting of P2 axons along the dorsoventral axis of the OB is controlled by Slit-3 expression PMID: 22981605
6. Study identify that the homeobox gene Nkx2-5 is required for early ventral restriction of Slit3 and that the T-box transcription factor Tbx2 mediates repression of Slit3 in nonchamber myocardium. PMID: 20941780
7. The chemorepellent Slit3 promotes monocyte migration. PMID: 21078908
8. During blood vessel development, Slit3 gene expression (and that of Slit2) are linked to posttranscriptional regulation of Robo receptors. PMID: 20947829
9. role in regulating development of the diaphragm PMID: 12702769
10. Experiments with triple mutant mice demonstrate a key role for Slit3 signaling in vertebrate midline commissural axon guidance. PMID: 15091338
11. Slit-3 and Robo-2 expression is restricted to specific, complementary subsets of mesenchyme PMID: 15162513
12. functions to promote angiogenesis in coordinating organogenesis during embryonic development PMID: 19741192
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亞細胞定位：

Secreted.
數據庫鏈接：

KEGG: mmu:20564

STRING: 10090.ENSMUSP00000066857

UniGene: Mm.478604