Recombinant Mouse Seizure 6-like protein 2 (Sez6l2), partial

中文名稱：

小鼠Sez6l2重組蛋白
貨號：

CSB-YP684153MO
規格：
來源：

Yeast
其他：

中文名稱：

小鼠Sez6l2重組蛋白
貨號：

CSB-EP684153MO
規格：
來源：

E.coli
其他：

中文名稱：

小鼠Sez6l2重組蛋白
貨號：

CSB-EP684153MO-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

小鼠Sez6l2重組蛋白
貨號：

CSB-BP684153MO
規格：
來源：

Baculovirus
其他：

中文名稱：

小鼠Sez6l2重組蛋白
貨號：

CSB-MP684153MO
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

Sez6l2
Uniprot No.：

Q4V9Z5
別名：

Sez6l2Seizure 6-like protein 2; Brain-specific receptor-like protein A; BSRP-A
種屬：

Mus musculus (Mouse)
蛋白長度：

Partial
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

May contribute to specialized endoplasmic reticulum functions in neurons.
基因功能參考文獻：
1. Sez6l2 is one of the auxiliary subunits of the AMPA receptor and acts as a scaffolding protein to link GluR1 to ADD. Furthermore, Sez6l2 overexpression upregulates ADD phosphorylation, whereas siRNA-mediated downregulation of Sez612 prevents ADD phosphorylation, suggesting that Sez6l2 modulates AMPA-ADD signal transduction. PMID: 29032200
2. Sez6l2 expression in mouse embryos was restricted to the spinal cord and brain PMID: 19242545
亞細胞定位：

Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Note=In cerebellar predominantly localized to the endoplasmic reticulum.
蛋白家族：

SEZ6 family
組織特異性：

Expressed exclusively in the brain, predominantly in the neurons. Wide expression in the gray matter of the brain with high levels in the olfactory bulb, anterior olfactory nuclei, hippocampal formation and cerebellar cortex. Detected diffusely and weakly
數據庫鏈接：

KEGG: mmu:233878

STRING: 10090.ENSMUSP00000101940

UniGene: Mm.283926